Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 16/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17014772 | 0.90 | AR (0.62) | ARNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL22291226 | 0.87 | AR (0.73) | ARNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL17014724 | 0.83 | AR (0.76) | ARNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL19051370 | 0.81 | AR (0.48) | ARNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL25649389 | 0.80 | AR (0.74) | ARNPC1RAB9ASMN1; SMN2MAPK1 | |
| SCHEMBL19051371 | 0.80 | AR (0.50) | ARNPC1RAB9ASMN1; SMN2MEN1 | |
| SCHEMBL25942616 | 0.78 | AR (0.71) | ARNPC1RAB9ASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL22263265 | 0.78 | AR (0.70) | ARNPC1RAB9ASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL30219483 | 0.78 | AR (0.70) | ARNPC1RAB9ASMN1; SMN2MAPK1 | |
| Hydrochloric Acid SCHEMBL22263280 | 0.78 | AR (0.70) | ARNPC1RAB9ASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015120543-A1 | HUMAN ANDROGEN RECEPTOR DNA-BINDING DOMAIN (DBD) COMPOUNDS AS THERAPEUTICS AND METHODS FOR THEIR USE | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2015-08-20 | — | — | WO | disclosed |