Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 19/20 | 1.00 |
| ▸ | KRAS | P01116 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17015113 | 0.88 | KCNN4 (1.00) | KCNN4 | |
| SCHEMBL17015119 | 0.80 | KCNN4 (0.76) | KCNN4 | |
| SCHEMBL17015095 | 0.79 | KCNN4 (1.00) | KCNN4 | |
| SCHEMBL17015115 | 0.77 | KCNN4 (1.00) | KCNN4 | |
| SCHEMBL17015107 | 0.74 | KCNN4 (1.00) | KCNN4 | |
| SCHEMBL17015070 | 0.68 | KCNN4 (1.00) | KCNN4 | |
| SCHEMBL17015111 | 0.68 | KCNN4 (1.00) | KCNN4 | |
| SCHEMBL17015054 | 0.67 | KCNN4 (1.00) | KCNN4 | |
| SCHEMBL17015058 | 0.66 | KCNN4 (1.00) | KCNN4 | |
| SCHEMBL30806295 | 0.66 | KCNN4 (0.50) | KCNN4KRASSOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9533999-B2 | Fused thiazin-3-ones as KCA3.1 inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-01-03 | — | — | US | disclosed |
| US-20150232484-A1 | FUSED THIAZIN-3-ONES AS KCA3.1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-08-20 | — | — | US | disclosed |
| US-20150232484-A1 | FUSED THIAZIN-3-ONES AS KCA3.1 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150232484-A1 | FUSED THIAZIN-3-ONES AS KCA3.1 INHIBITORS | KCNA3, KCNK3, KCNN3 | KCNN4 76/4885KRAS 2300/4885SOS1 3364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.