Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.55 |
| ▸ | CA2 | P00918 | 5/20 | 0.55 |
| ▸ | CA7 | P43166 | 4/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA4 | P22748 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27537639 | 0.91 | CA1 (0.53) | CA1CA2CA7CA9CA4 | |
| SCHEMBL30534 | 0.90 | — | — | |
| SCHEMBL6013926 | 0.90 | — | — | |
| SCHEMBL3093350 | 0.90 | — | — | |
| Methane SCHEMBL27945377 | 0.88 | CA1 (0.63) | CA1CA2CA7CA9CA4 | |
| SCHEMBL5925041 | 0.88 | CA1 (0.63) | CA1CA2CA7CA9CA4 | |
| SCHEMBL8754223 | 0.88 | CA1 (0.63) | CA1CA2CA7CA9CA4 | |
| SCHEMBL291913 | 0.88 | CA1 (0.63) | CA1CA2CA7CA9CA4 | |
| Hydrogen Sulfide SCHEMBL27334247 | 0.88 | CA1 (0.63) | CA1CA2CA7CA9CA4 | |
| Bicarbonate SCHEMBL10632366 | 0.86 | CA1 (0.57) | CA1CA2CA7CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130197038-A1 | Compositions And Methods For Neovascularization | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2013-08-01 | — | — | US | claimed |
| JP-60061030-A | — | — | None | — | — | JP | disclosed |
| US-10071110-B2 | Phosphonate compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-09-11 | — | — | US | disclosed |
| US-20170239279-A1 | PHOSPHONATE COMPOUNDS | UNIV CALIFORNIA (US) | 2017-08-24 | — | — | US | disclosed |
| US-9649321-B2 | Phosphonate compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-05-16 | — | — | US | disclosed |
| US-9446031-B2 | Compositions and methods for neovascularization | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2016-09-20 | — | — | US | disclosed |
| US-20160067268-A1 | PHOSPHONATE COMPOUNDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2016-03-10 | — | — | US | disclosed |
| US-9206208-B2 | Phosphonate compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-12-08 | — | — | US | disclosed |
| US-20150051174-A1 | Phosphonate Compounds | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-02-19 | — | — | US | disclosed |
| US-8889658-B2 | Phosphonate compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-11-18 | — | — | US | disclosed |
| US-6451952-B2 | POLYMERIZING ALLYL ETHER MONOMER IN PRESENCE OF HALOALKYL DIOXOLANE COMPOUND (BY-PRODUCT, IMPURITY); ANTISCALING AGENT WITH IMPROVED GELATION INHIBITION | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-09-17 | — | — | US | disclosed |
| EP-1233770-A2 | PHOSPHONATE COMPOUNDS | The Regents of The University of California at San Diego (US) | 2002-08-28 | — | — | EP | disclosed |
| US-20020049147-A1 | Novel water-soluble copolymer and its production process and use | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-04-25 | — | — | US | disclosed |
| EP-1182217-A2 | Novel water-soluble copolymer and its production process and use | Nippon Shokubai Co., Ltd. (JP) | 2002-02-27 | — | — | EP | disclosed |
| US-20020016430-A1 | Production process for allyl ether-based polymer | NIPPON SHOKUBAI CO., LTD. (JP) | 2002-02-07 | — | — | US | disclosed |
| EP-1158009-A2 | Production process for allyl ether-based polymer | Nippon Shokubai Co., Ltd. (JP) | 2001-11-28 | — | — | EP | disclosed |
| WO-2001039724-A2 | PHOSPHONATE COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, SAN DIEGO (US) | 2001-06-07 | — | — | WO | disclosed |
| JP-S6061030-A | EMULSIFYING SOLUBILIZER | NIPPON SAAFUAKUTANTO KOGYO KK | 1985-04-08 | — | — | JP | disclosed |
| US-4504409-A | ALKENYL OR ALKYL GLYCERYLETHER PHOSPHATE | KAO CORPORATION (JP) | 1985-03-12 | — | — | US | disclosed |
| US-4500693-A | OF (METH-)ACRYLIC ACID (OR SALT THEREOF) AND ALLYL ETHERSULFONATE | NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) | 1985-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150051174-A1 | Phosphonate Compounds | PHPT1, PHOSPHO1, PIK3CA | CA1 4092/4885CA2 3473/4885CA7 3176/4885 |
| US-10071110-B2 | Phosphonate compounds | PHPT1, PHOSPHO1, PIK3CA | CA1 4092/4885CA2 3473/4885CA7 3176/4885 |
| US-20170239279-A1 | PHOSPHONATE COMPOUNDS | PHPT1, PHOSPHO1, PIK3CA | CA1 4092/4885CA2 3473/4885CA7 3176/4885 |
| US-20160067268-A1 | PHOSPHONATE COMPOUNDS | PHPT1, PHOSPHO1, PIK3CA | CA1 4092/4885CA2 3473/4885CA7 3176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.