Sugi Predict

Sugi Predict / Compounds / Bicarbonate

Bicarbonate

Bicarbonate

SCHEMBL1701669

O=C(O)O.O=C(O)O.O=C(O)O.O=C(O)O.O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].O=C([O-])[O-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2]

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CA1 P00915 3/20 0.56
▸ CA2 P00918 1/20 0.56
▸ CA9 Q16790 1/20 0.56
▸ CA4 P22748 5/20 0.42
▸ FAHD1 Q6P587 1/20 0.42
▸ LMNA P02545 2/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ LDHA P00338 1/20 0.33
▸ BLM P54132 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ ACHE P22303 1/20 0.33
▸ FFAR3 O14843 1/20 0.33
▸ LCK P06239 1/20 0.33
▸ FYN P06241 1/20 0.33
▸ OR51E2 Q9H255 1/20 0.31
▸ CASP1 P29466 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL393266 1.00 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL7608551 1.00 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL8674948 1.00 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL16098384 1.00 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL10821897 1.00 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL5491026 1.00 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL11832999 1.00 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL9247439 1.00 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL4958654 1.00 CA1 (0.56) CA1CA2CA9CA4FAHD1
Bicarbonate SCHEMBL6562090 1.00 CA1 (0.56) CA1CA2CA9CA4FAHD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2588682-B1 GUTTER GUARD MESH SECURED USING ADHESIVE LEAF FREE PTY LTD (AU) 2015-07-22 — — EP claimed
CN-104592658-A Cold-resistant cable sheathing material ANHUI HONGYI CABLE GROUP CO LTD 2015-05-06 — — CN claimed
US-8572899-B1 Gutter guard mesh secured using adhesive LEAF FREE PTY LTD (AU) 2013-11-05 — — US claimed
EP-2588682-A1 GUTTER GUARD MESH SECURED USING ADHESIVE Leaf Free Pty Ltd (AU) 2013-05-08 — — EP claimed
WO-2012000051-A1 GUTTER GUARD MESH SECURED USING ADHESIVE LEAF FREE PTY LTD (AU) 2012-01-05 — — WO claimed
EP-2588682-B1 GUTTER GUARD MESH SECURED USING ADHESIVE LEAF FREE PTY LTD (AU) 2015-07-22 — — EP disclosed
CN-104592658-A Cold-resistant cable sheathing material ANHUI HONGYI CABLE GROUP CO LTD 2015-05-06 — — CN disclosed
US-20140013702-A1 Gutter Guard Mesh Secured Using Adhesive LEAF FREE PTY LTD (AU) 2014-01-16 — — US disclosed
US-8572899-B1 Gutter guard mesh secured using adhesive LEAF FREE PTY LTD (AU) 2013-11-05 — — US disclosed
EP-2588682-A1 GUTTER GUARD MESH SECURED USING ADHESIVE Leaf Free Pty Ltd (AU) 2013-05-08 — — EP disclosed
WO-2012000051-A1 GUTTER GUARD MESH SECURED USING ADHESIVE LEAF FREE PTY LTD (AU) 2012-01-05 — — WO disclosed
CN-101125058-B Antiskid carpet XIHU XUE 2010-07-28 — — CN disclosed
CN-101744509-A Skid resistant carpet SHANGHAI NANHUI AREA HUINANZHE 2010-06-23 — — CN disclosed
CN-101125058-A Antiskid carpet XIHU XUE (CN) 2008-02-20 — — CN disclosed