Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL393266 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL7608551 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL8674948 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL16098384 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL10821897 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL11832999 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL9247439 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL4958654 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL1701669 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL6562090 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107686608-A | Hollow glass micropearl blending and modifying PVB/ABS resin tiles and preparation method thereof | 秦皇岛市地维建材有限公司 | 2018-02-13 | — | — | CN | claimed |
| CN-107568743-A | A kind of vitamin calcium tablet | 南通荣成医药化工有限公司 | 2018-01-12 | — | — | CN | claimed |
| CN-107513366-A | A kind of oil resistant fluid sealant and preparation method thereof | 江苏天辰新材料股份有限公司 | 2017-12-26 | — | — | CN | claimed |
| CN-107362173-A | A kind of calcium tablet | 南通荣成医药化工有限公司 | 2017-11-21 | — | — | CN | claimed |
| CN-106281204-A | A kind of weather resistant buildings waterproof fluid sealant and preparation method thereof | 樊之雄 | 2017-01-04 | — | — | CN | claimed |
| CN-105459530-A | Processing method of multifunctional environment-friendly polyvinyl chloride composite decorative material | QINGDAO WEIYE FORGING MACHINERY CO LTD | 2016-04-06 | — | — | CN | claimed |
| CN-105368217-A | Waterproof type interior wall latex paint | TIANJIN YICHENGZEHENG SECURITY TECH DEV CO LTD | 2016-03-02 | — | — | CN | claimed |
| CN-105206322-A | High-temperature-prevention fire-resistant cable for computer | ANHUI HUAXING CABLE GROUP CO | 2015-12-30 | — | — | CN | claimed |
| CN-103436217-A | Single-component dealcoholized oil-resistant silicone sealant and preparation method thereof | JIANGSU TIANCHEN SILICON CO LTD | 2013-12-11 | — | — | CN | claimed |
| CN-102995501-B | Curtain type coating craft paper and preparation method thereof | JI AN GROUP CO LTD | 2013-11-20 | — | — | CN | claimed |
| CN-102218877-B | Processing method of multifunctional environment-friendly polyvinyl chloride composite decorative material | WUXI RUIYING SYNTHETIC LEATHER CO LTD | 2013-05-29 | — | — | CN | claimed |
| CN-102218877-A | Processing method of multifunctional environment-friendly polyvinyl chloride composite decorative material | WUXI RUIYING SYNTHETIC LEATHER CO LTD | 2011-10-19 | — | — | CN | claimed |
| CN-105925176-B | A kind of non-stick pan coating layer, preparation method and its non-stick pan | 宁波贝得厨具有限公司 | 2019-03-05 | — | — | CN | disclosed |
| CN-107686608-A | Hollow glass micropearl blending and modifying PVB/ABS resin tiles and preparation method thereof | 秦皇岛市地维建材有限公司 | 2018-02-13 | — | — | CN | disclosed |
| CN-107568743-A | A kind of vitamin calcium tablet | 南通荣成医药化工有限公司 | 2018-01-12 | — | — | CN | disclosed |
| CN-107513366-A | A kind of oil resistant fluid sealant and preparation method thereof | 江苏天辰新材料股份有限公司 | 2017-12-26 | — | — | CN | disclosed |
| EP-1027175-A1 | CLEANING COMPOSITION AND APPARATUS FOR REMOVING BIOFILM AND DEBRIS FROM LINES AND TUBING AND METHOD THEREFOR | Princeton Trade and Technology, Inc. (US) | 2000-08-16 | — | — | EP | disclosed |
| US-6027572-A | MIXING AN AQUEOUS CLEANING SOLUTION OF WATER AND ONE OR MORE SURFACTANTS, TOGETHER WITH A GAS UNDER PRESSURE TO CREATE A TURBULENT FLOW WITHIN THE TUBING THAT LOOSENS THE BIOFILM AND DEBRIS SO THEY CAN BE FLUSHED FROM THE TUBING | PRINCETON TRADE AND TECHNOLOGT, INC (US) | 2000-02-22 | — | — | US | disclosed |
| WO-1998058632-A1 | CLEANING COMPOSITION AND APPARATUS FOR REMOVING BIOFILM AND DEBRIS FROM LINES AND TUBING AND METHOD THEREFOR | PRINCETON TRADE AND TECHNOLOGY, INC. (US) | 1998-12-30 | — | — | WO | disclosed |
| US-5352158-A | Court surface | BRODEUR JR EDOUARD A (US) | 1994-10-04 | — | — | US | disclosed |