Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | HPGD | P15428 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.76 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.49 |
| ▸ | PDE5A | O76074 | 2/20 | 0.49 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5023086 | 0.91 | MEN1 (0.74) | MEN1MAPTHPGDBLMPMP22 | |
| SCHEMBL11531345 | 0.90 | MEN1 (0.72) | MEN1MAPTHPGDBLMPMP22 | |
| Etazolate SCHEMBL29824913 | 0.87 | MEN1 (0.98) | MEN1MAPTHPGDBLMPMP22 | |
| Etazolate SCHEMBL16703320 | 0.87 | MEN1 (0.98) | MEN1MAPTHPGDBLMPMP22 | |
| Etazolate SCHEMBL123105 | 0.86 | MEN1 (1.00) | MEN1MAPTHPGDBLMPMP22 | |
| Etazolate SCHEMBL1004450 | 0.85 | MEN1 (0.94) | MEN1MAPTHPGDBLMPMP22 | |
| Etazolate SCHEMBL16702579 | 0.85 | MEN1 (0.94) | MEN1MAPTHPGDBLMPMP22 | |
| SCHEMBL2459284 | 0.84 | MEN1 (0.79) | MEN1MAPTHPGDBLMPMP22 | |
| SCHEMBL13987138 | 0.81 | MEN1 (0.52) | MEN1MAPTHPGDBLMPMP22 | |
| SCHEMBL13987114 | 0.79 | PDE4B (0.54) | MEN1MAPTHPGDBLMPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150231149-A1 | SPERM FUNCTION/ACTIVITY | UNIVERSITY OF DUNDEE (GB) | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150231149-A1 | SPERM FUNCTION/ACTIVITY | PDE5A, PDE4A, PDE12 | MEN1 3507/4885MAPT 4626/4885HPGD 1474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.