SCHEMBL17017289

SCHEMBL17017289

CCCCCCCC/C=C/O[Si](C)(C)C(C)(C)C

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 4/20 0.39
TRPV1 Q8NER1 1/20 0.39
TSHR P16473 1/20 0.39
CYP1A2 P05177 3/20 0.37
CYP2C19 P33261 3/20 0.37
BLM P54132 3/20 0.37
HSD17B10 Q99714 3/20 0.37
GMNN O75496 2/20 0.37
USP2 O75604 2/20 0.37
POLB P06746 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP2C9 P11712 2/20 0.37
APEX1 P27695 2/20 0.37
RECQL P46063 2/20 0.37
CYP2D6 P10635 1/20 0.37
TERT O14746 3/20 0.35
MAPT P10636 2/20 0.35
FABP4 P15090 2/20 0.35
PTPN1 P18031 2/20 0.35
PPARG P37231 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18092328 1.00 FAAH (0.39) FAAHTRPV1TSHRCYP1A2CYP2C19
SCHEMBL31679616 0.84
SCHEMBL17017282 0.84
SCHEMBL18092326 0.80 FAAH (0.45) FAAHTRPV1CYP1A2CYP2C19BLM
SCHEMBL21551898 0.80 FAAH (0.45) FAAHTRPV1CYP1A2CYP2C19BLM
SCHEMBL18092325 0.80 FAAH (0.45) FAAHTRPV1CYP1A2CYP2C19BLM
SCHEMBL9875996 0.78
SCHEMBL9875993 0.78
SCHEMBL28949753 0.77 TSHR (0.37) TSHR
SCHEMBL14496881 0.76 LPAR2 (0.45) FAAHTRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9708236-B2 Terminal alkene monoisomerization catalysts and methods SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2017-07-18 US disclosed
US-9708236-B2 Terminal alkene monoisomerization catalysts and methods SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION (US) 2017-07-18 US disclosed
US-20150231621-A1 TERMINAL ALKENE MONOISOMERIZATION CATALYSTS AND METHODS SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION 2015-08-20 US disclosed
US-20150231621-A1 TERMINAL ALKENE MONOISOMERIZATION CATALYSTS AND METHODS SAN DIEGO STATE UNIVERSITY RESEARCH FOUNDATION 2015-08-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150231621-A1 TERMINAL ALKENE MONOISOMERIZATION CATALYSTS AND METHODS INF2, CPNE4, TEC FAAH 1507/4885TRPV1 2795/4885TSHR 3666/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.