Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | PGR | P06401 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | SNCA | P37840 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.45 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3599812 | 0.82 | ALOX5 (0.45) | TRPV1KMT2A | |
| SCHEMBL3599814 | 0.82 | ALOX5 (0.45) | TRPV1KMT2A | |
| Squalene SCHEMBL27795631 | 0.81 | KMT2A (0.65) | KMT2AMAPTPGRHTR1AADORA3 | |
| SCHEMBL16190235 | 0.81 | GGPS1 (0.64) | TRPV1MAPTGGPS1ALDH1A1CYP3A4 | |
| SCHEMBL3864833 | 0.81 | GGPS1 (0.64) | TRPV1MAPTGGPS1ALDH1A1CYP3A4 | |
| SCHEMBL8224019 | 0.80 | TRPV1 (0.55) | TRPV1KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL3595116 | 0.80 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL3595119 | 0.80 | TRPV1 (0.46) | TRPV1 | |
| SCHEMBL17019884 | 0.80 | GGPS1 (0.52) | TRPV1MAPTGGPS1CYP3A4 | |
| SCHEMBL28652919 | 0.79 | GGPS1 (0.64) | TRPV1MAPTGGPS1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10376591-B2 | Formulations and carrier systems including farnesylthiosalicylic moieties | University of Pittsburgh—of the Commonwealth System of Higher Education (US) | 2019-08-13 | — | — | US | disclosed |
| US-20150231271-A1 | FORMULATIONS AND CARRIER SYSTEMS INCLUDING FARNESYLTHIOSALYCYLIC MOITIES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10376591-B2 | Formulations and carrier systems including farnesylthiosalicylic moieties | FNTA, FNTB, KRAS | TRPV1 1417/4885KMT2A 4722/4885MAPT 4139/4885 |
| US-20150231271-A1 | FORMULATIONS AND CARRIER SYSTEMS INCLUDING FARNESYLTHIOSALYCYLIC MOITIES | FNTA, MSR1, NPC1L1 | TRPV1 1470/4885KMT2A 4619/4885MAPT 4047/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.