Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12224689 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL16546825 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL13566394 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL12508099 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL274348 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL11570949 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL12082008 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL16546834 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL3425470 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL11969800 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024043319-A1 | ANTIBODY-DRUG COMPLEX | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2024-02-29 | — | — | WO | disclosed |
| US-9476885-B2 | Water-dispersable nanoparticles | Life Technologies Corporation (US) | 2016-10-25 | — | — | US | disclosed |
| US-20150233936-A1 | WATER-DISPERSABLE NANOPARTICLES | Life Technologies Corporation | 2015-08-20 | — | — | US | disclosed |