Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12224689 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL16546825 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL13566394 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL12508099 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL274348 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL11570949 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL17021464 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL16546834 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL3425470 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 | |
| SCHEMBL11969800 | 1.00 | TSHR (0.39) | TSHRCYP3A4CA2HSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230158141-A1 | Conjugates of Biomolecule and Use Thereof | YAFEI SHANGHAI BIOLOG MEDICINE SCIENCE & TECHNOLOG (CN) | 2023-05-25 | — | — | US | disclosed |
| EP-3419420-B1 | LECITHIN-BASED SPRAY ADJUVANT CONTAINING ORGANOSILICON WETTING AGENTS | MOMENTIVE PERFORMANCE MAT INC (US) | 2022-06-22 | — | — | EP | disclosed |
| WO-2017210009-A1 | PHOTOLABILE COMPOSITIONS AS A STABILIZATION PLATFORM | NANOLY BIOSCIENCE, INC. (US) | 2017-12-07 | — | — | WO | disclosed |
| US-8927674-B2 | Dehydrogenative silylation and crosslinking using cobalt catalysts | PRINCETON UNIVERSITY (US) | 2015-01-06 | — | — | US | disclosed |
| US-20140051822-A1 | Dehydrogenative Silylation and Crosslinking Using Cobalt Catalysts | PRINCETON UNIVERSITY (US) | 2014-02-20 | — | — | US | disclosed |
| US-8258259-B2 | Macromolecular compounds having controlled stoichiometry | STARPHARMA PTY LIMITED (AU) | 2012-09-04 | — | — | US | disclosed |
| US-20090118467-A1 | Macromolecular Compounds Having Controlled Stoichiometry | STARPHARMA PTY LIMITED (AU) | 2009-05-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118467-A1 | Macromolecular Compounds Having Controlled Stoichiometry | MICA, PICALM, CLTB | TSHR 3447/4885CYP3A4 3414/4885CA2 3784/4885 |
| US-20140051822-A1 | Dehydrogenative Silylation and Crosslinking Using Cobalt Catalysts | SIRT4, SIRT3, SIRT2 | TSHR 3489/4885CYP3A4 156/4885CA2 1565/4885 |
| US-20230158141-A1 | Conjugates of Biomolecule and Use Thereof | CD47, FCGR2A, CD40 | TSHR 782/4885CYP3A4 4599/4885CA2 1923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.