SCHEMBL1702174

SCHEMBL1702174

CCCCN(CC)C(=S)OCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 9/20 0.52
CA1 P00915 9/20 0.52
CA9 Q16790 9/20 0.52
CA2 P00918 7/20 0.52
ALDH1A1 P00352 2/20 0.45
ALDH2 P05091 2/20 0.45
MGLL Q99685 2/20 0.44
MMP1 P03956 1/20 0.34
MMP2 P08253 1/20 0.34
MMP3 P08254 1/20 0.34
MMP8 P22894 1/20 0.34
ABCB11 O95342 2/20 0.33
HTT P42858 2/20 0.33
GSDMD P57764 2/20 0.33
EHMT2 Q96KQ7 2/20 0.33
EHMT1 Q9H9B1 2/20 0.33
CYP2E1 P05181 1/20 0.33
PTGS1 P23219 1/20 0.33
CA4 P22748 1/20 0.33
CYP1A2 P05177 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9715892 0.88 CA12 (0.44) CA12CA1CA9CA2ALDH1A1
SCHEMBL9320867 0.86 CA12 (0.53) CA12CA1CA9CA2ALDH1A1
SCHEMBL965514 0.85 ALDH1A1 (0.50) CA12CA1CA9CA2ALDH1A1
SCHEMBL8772643 0.85 ALDH1A1 (0.42) CA12CA1CA9CA2ALDH1A1
SCHEMBL9873801 0.83 ALDH1A1 (0.48) CA12CA1CA9CA2ALDH1A1
SCHEMBL15173121 0.82 CA12 (0.52) CA12CA1CA9CA2ALDH1A1
SCHEMBL1701165 0.79 CA12 (0.48) CA12CA1CA9CA2ALDH1A1
SCHEMBL6687736 0.78 CA12 (0.53) CA12CA1CA9CA2ALDH1A1
SCHEMBL28502704 0.78 EHMT2 (0.34) CA12CA1CA9CA2ALDH1A1
SCHEMBL1902074 0.77 ALDH1A1 (0.42) CA12CA1CA9CA2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012003441-A1 SELF-EMULSIFYING OIL ISP INVESTMENTS INC. (US) 2012-01-05 WO disclosed
US-5308830-A Low dosage; nonphytotoxic to crops; pre- and postemergence ROHM AND HAAS COMPANY (US) 1994-05-03 US disclosed
US-5304531-A Preemergent, postemergent, controls weed growth 2-chloro-4-trifluoromethyl-3' (1-(carboethoxy) ethoxycarbonyl)-4-nitrodiphenyl ether BASF CORPORATION 1994-04-19 US disclosed
US-5290756-A Herbicides ROHM AND HAAS COMPANY (US) 1994-03-01 US disclosed
US-5272128-A Phosphosulfonate herbicides ROHM AND HAAS COMPANY (US) 1993-12-21 US disclosed
US-5215774-A Microwave ovens THE PILLSBURY COMPANY (US) 1993-06-01 US disclosed
US-5214190-A Nitrophenyl ether herbicides JOHNSON WAYNE O (US) 1993-05-25 US disclosed
US-4894479-A CARBONYLOXYAMINO DERIVATIVES ROHM AND HAAS COMPANY (US) 1990-01-16 US disclosed
US-4877897-A HERBICIDES ROHM AND HAAS COMPANY (US) 1989-10-31 US disclosed
US-4863507-A Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1989-09-05 US disclosed
US-4686294-A 1,3,4-thiadiazolyl ureas and processes for controlling weeds and wild grasses therewith CIBA-GEIGY CORPORATION (US) 1987-08-11 US disclosed
US-4439229-A Substituted phthalimides herbicides ROHM AND HAAS COMPANY (US) 1984-03-27 US disclosed
US-4386954-A Herbicidal diphenyl ethers ROHM AND HAAS COMPANY (US) 1983-06-07 US disclosed
EP-0068822-A2 Novel heterocyclic substituted benzenes, herbicidal compositions containing them and the use thereof for combating weeds ROHM AND HAAS COMPANY (US) 1983-01-05 EP disclosed
EP-0020052-A1 Novel substituted nitrodiphenyl ethers, herbicidal compositions containing them, processes for the preparation thereof and the use thereof for combating weeds ROHM AND HAAS COMPANY (US) 1980-12-10 EP disclosed