⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15984784 | 1.00 | — | — | |
| SCHEMBL7175341 | 1.00 | — | — | |
| SCHEMBL2610292 | 1.00 | — | — | |
| SCHEMBL12993494 | 1.00 | — | — | |
| SCHEMBL14607766 | 1.00 | — | — | |
| SCHEMBL19739056 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL17980412 | 0.96 | — | — | |
| SCHEMBL18558157 | 0.84 | THRB (0.35) | — | |
| SCHEMBL4149556 | 0.82 | — | — | |
| SCHEMBL21287450 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11053221-B2 | Substituted pyrimidines for inhibiting embryonic leucine zipper kinase activity | ARRIEN PHARMACEUTICALS LLC (US) | 2021-07-06 | — | — | US | disclosed |
| US-20200131154-A1 | PYRAZOLYL COMPOUNDS AND METHODS OF USE THEREOF | ARRIEN PHARMACEUTICALS LLC | 2020-04-30 | — | — | US | disclosed |
| US-20170362191-A1 | Substituted Cyclohexylamine Compounds | Epizyme, Inc. (US) | 2017-12-21 | — | — | US | disclosed |
| EP-2664625-B1 | Blood-brain barrier permeable peptide compositions | ICB INT INC (US) | 2017-08-23 | — | — | EP | disclosed |
| US-9296807-B2 | Method for expression of specific gene | TAKARA BIO INC. (JP) | 2016-03-29 | — | — | US | disclosed |
| US-20150232530-A1 | METHOD FOR EXPRESSION OF SPECIFIC GENE | TAKARA BIO INC. (JP) | 2015-08-20 | — | — | US | disclosed |