SCHEMBL1702238

SCHEMBL1702238

CCc1cccc(N(c2ccccc2)c2ccc(-c3ccc(N(c4ccccc4)c4cccc(CC)c4)cc3)cc2)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 15/20 0.48
BCL2 P10415 1/20 0.47
TP53 P04637 2/20 0.46
PTGS2 P35354 1/20 0.43
CYP2D6 P10635 2/20 0.41
MAPT P10636 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
KDM4E B2RXH2 1/20 0.41
ALDH1A1 P00352 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
TSHR P16473 2/20 0.40
THPO P40225 1/20 0.40
MTOR P42345 1/20 0.40
MEN1 O00255 1/20 0.39
LMNA P02545 1/20 0.39
PMP22 Q01453 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4576079 1.00 SIGMAR1 (0.48) SIGMAR1BCL2TP53PTGS2CYP2D6
SCHEMBL17986879 0.98 BCL2 (0.50) SIGMAR1BCL2TP53PTGS2CYP2D6
SCHEMBL12533849 0.98 BCL2 (0.50) SIGMAR1BCL2TP53PTGS2CYP2D6
SCHEMBL8141783 0.96 SIGMAR1 (0.46) SIGMAR1BCL2TP53PTGS2CYP2D6
SCHEMBL17678530 0.96 BCL2 (0.46) SIGMAR1BCL2TP53PTGS2
SCHEMBL13580186 0.95 BCL2 (0.51) SIGMAR1BCL2TP53PTGS2
SCHEMBL76603 0.94 TP53 (0.52) SIGMAR1TP53CYP2D6MAPTTDP1
SCHEMBL13136839 0.94 TP53 (0.52) SIGMAR1TP53CYP2D6MAPTTDP1
SCHEMBL14114271 0.93 BCL2 (0.44) SIGMAR1BCL2PTGS2
SCHEMBL12957222 0.92 TP53 (0.54) SIGMAR1TP53CYP2D6MAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150037732-A1 METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2015-02-05 US claimed
US-7267917-B2 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2007-09-11 US claimed
US-20060063080-A1 Photoreceptor charge transport layer composition XEROX CORPORATION (US) 2006-03-23 US claimed
US-11393990-B2 Quantum dot light emitting device and display apparatus including the same LG DISPLAY CO., LTD. (KR) 2022-07-19 US disclosed
US-20200058884-A1 QUANTUM DOT LIGHT EMITTING DEVICE AND DISPLAY APPARATUS INCLUDING THE SAME LG DISPLAY CO., LTD. (KR) 2020-02-20 US disclosed
US-20150037732-A1 METHOD FOR MANUFACTURING PHOTORECEPTOR LAYERS XEROX CORPORATION (US) 2015-02-05 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-8216759-B2 Electrophotographic carrier and use thereof SHARP KABUSHIKI KAISHA (JP) 2012-07-10 US disclosed
US-8216759-B2 Electrophotographic carrier and use thereof SHARP KABUSHIKI KAISHA (JP) 2012-07-10 US disclosed
EP-1089130-B1 Process for fabricating an electrophotographic imaging member XEROX CORP (US) 2012-04-18 EP disclosed
US-4880715-A Imaging system XEROX CORPORATION (US) 1989-11-14 US disclosed
US-4853307-A Imaging member containing a copolymer of styrene and ethyl acrylate XEROX CORPORATION (US) 1989-08-01 US disclosed
EP-0149328-B1 MIGRATION IMAGING MEMBER AND METHOD XEROX CORPORATION (US) 1988-06-01 EP disclosed
US-4536458-A Migration imaging system XEROX CORPORATION (US) 1985-08-20 US disclosed
US-4536457-A Migration imaging process XEROX CORPORATION (US) 1985-08-20 US disclosed
EP-0149328-A1 Migration imaging member and method XEROX CORPORATION (US) 1985-07-24 EP disclosed
US-4515882-A CHARGE TRANSFER COMPOUNDS AND CHARGE INJECTION ENABLING PARTICLES XEROX CORPORATION (US) 1985-05-07 US disclosed
US-4346158-A Imaging system with a diamine charge transport material in a polycarbonate resin XEROX CORPORATION (US) 1982-08-24 US disclosed
US-4265990-A Imaging system with a diamine charge transport material in a polycarbonate resin XEROX CORPORATION (US) 1981-05-05 US disclosed