SCHEMBL17022506

SCHEMBL17022506

Clc1nc(Br)nc2c1sc1ccccc12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LIMK1 P53667 1/20 0.41
▸ CDK5 Q00535 1/20 0.41
▸ CDK5R1 Q15078 1/20 0.41
▸ MAPT P10636 3/20 0.39
▸ TNKS O95271 2/20 0.39
▸ TNKS2 Q9H2K2 2/20 0.39
▸ PIM1 P11309 1/20 0.39
▸ PIM2 Q9P1W9 1/20 0.39
▸ KRAS P01116 1/20 0.39
▸ NPSR1 Q6W5P4 2/20 0.39
▸ MEN1 O00255 1/20 0.39
▸ HTT P42858 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ HRH4 Q9H3N8 1/20 0.38
▸ GPR3 P46089 1/20 0.38
▸ EGFR P00533 2/20 0.37
▸ KDM4E B2RXH2 1/20 0.36
▸ EGLN1 Q9GZT9 1/20 0.35
▸ LOXL2 Q9Y4K0 1/20 0.35
▸ RXFP1 Q9HBX9 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2534139 0.83 LIMK1 (0.44) LIMK1CDK5CDK5R1MAPTTNKS
SCHEMBL2497988 0.80 HRH4 (0.53) LIMK1CDK5CDK5R1MAPTTNKS
SCHEMBL17022477 0.78 MEN1 (0.46) LIMK1CDK5CDK5R1MAPTTNKS
SCHEMBL29888780 0.78 MEN1 (0.46) LIMK1CDK5CDK5R1MAPTTNKS
SCHEMBL17695023 0.78 TNKS (0.40) LIMK1CDK5CDK5R1MAPTTNKS
SCHEMBL15766144 0.77 LIMK1 (0.45) LIMK1CDK5CDK5R1MAPTTNKS
SCHEMBL24222727 0.76 TNKS (0.45) LIMK1CDK5CDK5R1MAPTTNKS
SCHEMBL26266691 0.75 MEN1 (0.44) LIMK1CDK5CDK5R1MAPTTNKS
SCHEMBL7215827 0.72 LIMK1 (0.65) LIMK1CDK5CDK5R1NPSR1HRH4
SCHEMBL18666124 0.72 LIMK1 (0.39) LIMK1CDK5CDK5R1MAPTTNKS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2910555-B1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2019-03-27 — — EP disclosed
EP-2910555-B1 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORP (US) 2019-03-27 — — EP disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 — — US disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 — — US disclosed
US-9502656-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-11-22 — — US disclosed
US-20150243893-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 — — US disclosed
US-20150243893-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 — — US disclosed
US-20150243893-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2015-08-27 — — US disclosed
EP-2910555-A1 Organic electroluminescent materials and devices Universal Display Corporation (US) 2015-08-26 — — EP disclosed
EP-2910555-A1 Organic electroluminescent materials and devices Universal Display Corporation (US) 2015-08-26 — — EP disclosed
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