SCHEMBL17695023

SCHEMBL17695023

Brc1nc(-c2ccccc2)c2sc3ccccc3c2n1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TNKS O95271 3/20 0.40
▸ TNKS2 Q9H2K2 3/20 0.40
▸ PIM1 P11309 2/20 0.40
▸ PIM2 Q9P1W9 2/20 0.40
▸ LIMK1 P53667 3/20 0.40
▸ CDK5 Q00535 1/20 0.40
▸ CDK5R1 Q15078 1/20 0.40
▸ KRAS P01116 1/20 0.37
▸ MAPT P10636 4/20 0.37
▸ ALDH1A1 P00352 1/20 0.37
▸ CYP1A2 P05177 1/20 0.37
▸ CYP2D6 P10635 1/20 0.37
▸ CYP2C19 P33261 1/20 0.37
▸ HRH4 Q9H3N8 1/20 0.36
▸ EGFR P00533 4/20 0.36
▸ MEN1 O00255 2/20 0.36
▸ KMT2A Q03164 2/20 0.36
▸ NPSR1 Q6W5P4 2/20 0.36
▸ LMNA P02545 1/20 0.36
▸ MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30333314 0.83 MEN1 (0.43) TNKSTNKS2PIM1PIM2LIMK1
SCHEMBL18370214 0.83 MEN1 (0.43) TNKSTNKS2PIM1PIM2LIMK1
SCHEMBL31192065 0.81 CYP1B1 (0.43) TNKSTNKS2LIMK1CDK5CDK5R1
SCHEMBL23327832 0.81 CYP1B1 (0.43) TNKSTNKS2LIMK1CDK5CDK5R1
SCHEMBL20068415 0.81 CYP1B1 (0.43) TNKSTNKS2LIMK1CDK5CDK5R1
SCHEMBL18017854 0.81 MEN1 (0.45) TNKSTNKS2PIM1PIM2LIMK1
SCHEMBL19169895 0.81 TNKS (0.46) TNKSTNKS2PIM1PIM2LIMK1
SCHEMBL16902632 0.81 ALDH1A1 (0.47) TNKSTNKS2PIM1PIM2LIMK1
SCHEMBL18017848 0.81 MEN1 (0.45) TNKSTNKS2PIM1PIM2LIMK1
SCHEMBL19413003 0.81 TNKS (0.40) TNKSTNKS2PIM1PIM2LIMK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230380280-A1 ORGANIC COMPOUNDS, MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-23 — — US disclosed
US-20230380280-A1 ORGANIC COMPOUNDS, MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-23 — — US disclosed
US-20230357169-A1 ORGANIC COMPOUNDS, MIXTURES, AND USES THEREOF IN ORGANIC ELETRONIC DEVICES Zhejiang Brilliant Optoelectronic Technology Co.,Ltd. (CN) 2023-11-09 — — US disclosed
US-11678574-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-06-13 — — US disclosed
US-11678574-B2 Compound and organic light emitting diode comprising same LG CHEM, LTD. (KR) 2023-06-13 — — US disclosed
US-9780312-B2 Carbazole-based compound and organic light emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-10-03 — — US disclosed
US-9780312-B2 Carbazole-based compound and organic light emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-10-03 — — US disclosed
US-20160118600-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-04-28 — — US disclosed
US-20160118600-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-04-28 — — US disclosed
US-20160111657-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-04-21 — — US disclosed
US-20160111657-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2016-04-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230357169-A1 ORGANIC COMPOUNDS, MIXTURES, AND USES THEREOF IN ORGANIC ELETRONIC DEVICES SLCO1B3, SLCO2B1, SLCO2A1 TNKS 4273/4885TNKS2 4512/4885PIM1 1003/4885
US-11678574-B2 Compound and organic light emitting diode comprising same CYP1A1, ARL1, ALDH1A1 TNKS 4133/4885TNKS2 4039/4885PIM1 2787/4885
US-20160118600-A1 CONDENSED CYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME CRY1, CCNT1, CRY2 TNKS 2951/4885TNKS2 3710/4885PIM1 2673/4885
US-20230380280-A1 ORGANIC COMPOUNDS, MIXTURES AND APPLICATIONS THEREOF IN ORGANIC ELECTRONIC DEVICES OR10J3, AOX1, SLCO4C1 TNKS 4443/4885TNKS2 4685/4885PIM1 899/4885
US-20160111657-A1 CARBAZOLE-BASED COMPOUND AND ORGANIC LIGHT EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CYP1B1 TNKS 2340/4885TNKS2 3422/4885PIM1 190/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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