⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22012650 | 0.85 | — | — | |
| SCHEMBL15025708 | 0.79 | LMNA (0.53) | — | |
| SCHEMBL765348 | 0.79 | — | — | |
| SCHEMBL114113 | 0.79 | — | — | |
| SCHEMBL29728513 | 0.79 | LMNA (0.58) | — | |
| Hydrochloric Acid SCHEMBL6600511 | 0.77 | LMNA (0.45) | — | |
| SCHEMBL17797345 | 0.77 | — | — | |
| SCHEMBL7354254 | 0.77 | — | — | |
| SCHEMBL7354257 | 0.77 | — | — | |
| SCHEMBL23175047 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120088763-A1 | TRIAZOLOPYRIDINE DERIVATIVES AND THEIR THERAPEUTIC USE | CHIESI FARMACEUTICI S.P.A. (IT) | 2012-04-12 | — | — | US | disclosed |