Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | KRAS | P01116 | 1/20 | 0.30 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL407038 | 0.88 | SLC6A2 (0.36) | KDM4EALDH1A1HPGDHSD17B10CYP2D6 | |
| SCHEMBL406421 | 0.88 | SLC6A4 (0.48) | KDM4EALDH1A1HPGDHSD17B10CYP2D6 | |
| SCHEMBL407204 | 0.76 | SLC6A2 (0.42) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL400946 | 0.76 | SLC6A4 (0.52) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL405209 | 0.69 | SLC6A2 (0.54) | KDM4EALDH1A1HPGDHSD17B10SLC6A2 | |
| SCHEMBL23980607 | 0.66 | KDM4E (0.53) | KDM4EALDH1A1HPGDHSD17B10ACHE | |
| SCHEMBL403660 | 0.65 | ALDH1A1 (0.38) | KDM4EALDH1A1HPGDHSD17B10SLC6A2 | |
| SCHEMBL406242 | 0.65 | SLC6A4 (0.49) | KDM4EHPGDCYP2D6SLC6A2SLC6A4 | |
| SCHEMBL29919905 | 0.62 | NQO1 (0.67) | KDM4EALDH1A1HPGDHSD17B10ACHE | |
| SCHEMBL8393507 | 0.62 | NQO1 (0.67) | KDM4EALDH1A1HPGDHSD17B10ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285787-B1 | 3-SUBSTITUTED PROPANAMINE COMPOUNDS | SK BIOPHARMACEUTICALS CO LTD (KR) | 2015-08-26 | — | — | EP | disclosed |