Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | HTR5A | P47898 | 1/20 | 0.31 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL406242 | 0.87 | SLC6A4 (0.49) | CYP2D6SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL407648 | 0.87 | TDP1 (0.36) | CYP2D6SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL17023206 | 0.77 | KDM4E (0.38) | CYP2D6SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL407759 | 0.69 | SLC6A4 (0.55) | CYP2D6SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL404655 | 0.69 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL400946 | 0.68 | SLC6A4 (0.52) | CYP2D6SLC6A2SLC6A4SLC6A3KMT2A | |
| SCHEMBL407204 | 0.68 | SLC6A2 (0.42) | CYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20625126 | 0.67 | KDM4E (0.52) | HPGDKMT2AKDM4EMEN1ALDH1A1 | |
| SCHEMBL406421 | 0.65 | SLC6A4 (0.48) | CYP2D6SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL407038 | 0.65 | SLC6A2 (0.36) | CYP2D6SLC6A2SLC6A4SLC6A3HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2285787-B1 | 3-SUBSTITUTED PROPANAMINE COMPOUNDS | SK BIOPHARMACEUTICALS CO LTD (KR) | 2015-08-26 | — | — | EP | disclosed |