Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.43 |
| ▸ | BRD2 | P25440 | 1/20 | 0.43 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.43 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 7/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20962760 | 0.93 | GAA (0.45) | KDM4ETDP1BRD4BRD2BRD3 | |
| SCHEMBL17023894 | 0.88 | GAA (0.50) | KDM4ETDP1BRD4BRD2BRD3 | |
| SCHEMBL17023905 | 0.86 | BRD4 (0.43) | KDM4ETDP1BRD4BRD2BRD3 | |
| SCHEMBL25787087 | 0.86 | KMT2A (0.56) | KDM4ETDP1BRD4BRD2BRD3 | |
| SCHEMBL17023877 | 0.86 | GAA (0.46) | KDM4ETDP1BRD4BRD2BRD3 | |
| SCHEMBL17023884 | 0.85 | GAA (0.43) | KDM4ETDP1BRD4BRD2BRD3 | |
| SCHEMBL17023881 | 0.84 | GAA (0.47) | KDM4ETDP1BRD4BRD2BRD3 | |
| SCHEMBL17023897 | 0.84 | KDM4E (0.50) | KDM4ETDP1BRD4BRD2BRD3 | |
| SCHEMBL17023872 | 0.84 | BRD4 (0.41) | KDM4ETDP1BRD4BRD2BRD3 | |
| SCHEMBL23926375 | 0.81 | BAZ2B (0.45) | KDM4ETDP1BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10847726-B2 | Imidizo derivatives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2020-11-24 | — | — | US | disclosed |
| US-10847726-B2 | Imidizo derivatives | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2020-11-24 | — | — | US | disclosed |
| US-20190131538-A1 | IMIDIZO DERIVATIVES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2019-05-02 | — | — | US | disclosed |
| US-20190131538-A1 | IMIDIZO DERIVATIVES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY | 2019-05-02 | — | — | US | disclosed |
| US-20150243896-A1 | IMIDAZO DERIVATIVES | ARMY, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2015-08-27 | — | — | US | disclosed |
| US-20150243896-A1 | IMIDAZO DERIVATIVES | ARMY, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2015-08-27 | — | — | US | disclosed |
| US-20150243896-A1 | IMIDAZO DERIVATIVES | ARMY, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE | 2015-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190131538-A1 | IMIDIZO DERIVATIVES | IKZF1, IKZF3, IKZF2 | KDM4E 1297/4885TDP1 3316/4885BRD4 96/4885 |
| US-10847726-B2 | Imidizo derivatives | IKZF1, IKZF3, IKZF2 | KDM4E 1297/4885TDP1 3316/4885BRD4 96/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.