Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.38 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17088165 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1LMNAMEN1 | |
| SCHEMBL29023770 | 1.00 | TSHR (0.50) | TSHRTHRBALDH1A1LMNAMEN1 | |
| SCHEMBL10594325 | 0.97 | TSHR (0.47) | TSHRTHRBALDH1A1LMNAMEN1 | |
| SCHEMBL15520743 | 0.97 | TSHR (0.44) | TSHRTHRBALDH1A1LMNAMEN1 | |
| SCHEMBL9746825 | 0.91 | TSHR (0.39) | TSHRTHRBALDH1A1LMNAMEN1 | |
| SCHEMBL27514135 | 0.88 | TSHR (0.44) | TSHRTHRBALDH1A1LMNAMEN1 | |
| SCHEMBL1828102 | 0.87 | TSHR (0.40) | TSHRTHRBALDH1A1LMNAMEN1 | |
| SCHEMBL1829570 | 0.81 | — | — | |
| SCHEMBL6841034 | 0.81 | TSHR (0.50) | TSHRTHRBALDH1A1LMNAMEN1 | |
| SCHEMBL6841496 | 0.81 | TSHR (0.50) | TSHRTHRBALDH1A1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150244028-A1 | NONAQUEOUS SECONDARY CELL, AND FIRE-RETARDANT AGENT AND ADDITIVE FOR NONAQUEOUS SECONDARY CELL | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 2015-08-27 | — | — | US | disclosed |