SCHEMBL1828102

SCHEMBL1828102

CCCC[SiH](O)CCCC

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
LMNA P02545 3/20 0.40
ALDH1A1 P00352 3/20 0.39
THRB P10828 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CES2 O00748 5/20 0.33
CES1 P23141 5/20 0.33
ANPEP P15144 1/20 0.33
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32
NOS2 P35228 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
AKR1B1 P15121 1/20 0.30
TP53 P04637 1/20 0.30
SLC22A2 O15244 1/20 0.30
SLC22A1 O15245 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1829570 0.94
Benzene SCHEMBL28857166 0.91 TSHR (0.33) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL15520743 0.90 TSHR (0.44) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL1829074 0.87
SCHEMBL17024461 0.87 TSHR (0.50) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL17088165 0.87 TSHR (0.50) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL16199823 0.86 DNM1 (0.46) TSHRLMNAALDH1A1MEN1KMT2A
SCHEMBL9746825 0.84 TSHR (0.39) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL970152 0.79
SCHEMBL1827792 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113529417-B Water-based organic silicon permeable anti-corrosion impregnant and preparation method thereof 中交上海三航科学研究院有限公司 2023-06-30 CN claimed
CN-113529417-A Water-based organic silicon permeation type anti-corrosion impregnant and preparation method thereof 中交上海三航科学研究院有限公司 2021-10-22 CN claimed
CN-113966350-B Modified vinyl aromatic copolymer, process for producing the same, modified conjugated diene copolymer, and use of the same 日铁化学材料株式会社 2025-03-18 CN disclosed
US-12173098-B2 Modified vinylaromatic copolymer, production method therefor, modified conjugated diene copolymer obtained therefrom and composition thereof, crosslinked rubber object, and tire member NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2024-12-24 US disclosed
CN-113529417-B Water-based organic silicon permeable anti-corrosion impregnant and preparation method thereof 中交上海三航科学研究院有限公司 2023-06-30 CN disclosed
US-20230102867-A1 MODIFIED VINYLAROMATIC COPOLYMER, PRODUCTION METHOD THEREFOR, MODIFIED CONJUGATED DIENE COPOLYMER OBTAINED THEREFROM AND COMPOSITION THEREOF, CROSSLINKED RUBBER OBJECT, AND TIRE MEMBER NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2023-03-30 US disclosed
WO-2022129201-A1 PLATELET-LIKE MATTING AGENT FOR POWDER COATING AND POWDER COATINGS ECKART GMBH (DE) 2022-06-23 WO disclosed
EP-4005819-A1 MODIFIED VINYLAROMATIC COPOLYMER, PRODUCTION METHOD THEREFOR, MODIFIED CONJUGATED-DIENE COPOLYMER OBTAINED THEREFROM AND COMPOSITION THEREOF, CROSSLINKED RUBBER OBJECT, AND TIRE MEMBER Nippon Steel Chemical & Material Co., Ltd. (JP) 2022-06-01 EP disclosed
CN-113966350-A Modified vinyl aromatic copolymer and method for producing same, modified conjugated diene copolymer obtained therefrom, composition of modified conjugated diene copolymer, crosslinked rubber, and tire member 日铁化学材料株式会社 2022-01-21 CN disclosed
CN-113529417-A Water-based organic silicon permeation type anti-corrosion impregnant and preparation method thereof 中交上海三航科学研究院有限公司 2021-10-22 CN disclosed
EP-2698403-B1 Surface modified pearlescent pigments and their use in powder coatings ECKART GMBH (DE) 2018-01-03 EP disclosed
EP-1840115-A2 Process for the preparation of vinyl- or allyl-containing compounds Daicel Chemical Industries, Ltd. (JP) 2007-10-03 EP disclosed
US-20070213549-A1 Process for the preparation of vinyl- or allyl-containing compounds DAICEL CHEMICAL INDUSTRIES, LTD. 2007-09-13 US disclosed
US-5415988-A Hydroquinone-type additive FUJI PHOTO FILM CO., LTD. (JP) 1995-05-16 US disclosed
EP-0438148-A2 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1991-07-24 EP disclosed
US-4959300-A Silver halide photographic light-sensitive material with improved gradation balance KONICA CORPORATION (JP) 1990-09-25 US disclosed
EP-0159568-B1 THE USE OF HIGHER ALKYL MODIFIED TERPOLYMERIC SILICONES AS FIBER OR TEXTILE FINISHES UNION CARBIDE CORPORATION (US) 1989-08-30 EP disclosed
EP-0287090-A2 Silver halide photopraphic lightsensitive material with improved gradation balance KONICA CORPORATION (JP) 1988-10-19 EP disclosed
US-4661405-A Textiles treated with higher alkyl modified epoxy terpolymeric silicones UNION CARBIDE CORPORATION (US) 1987-04-28 US disclosed
EP-0159568-A2 The use of higher alkyl modified terpolymeric silicones as fiber or textile finishes UNION CARBIDE CORPORATION (US) 1985-10-30 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070213549-A1 Process for the preparation of vinyl- or allyl-containing compounds ESRRB, NR0B2, ESRRA TSHR 968/4885LMNA 3885/4885ALDH1A1 1891/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.