Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251998 | 0.97 | LMNA (0.43) | LMNAMEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL5819428 | 0.90 | MEN1 (0.50) | LMNAMEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL28830113 | 0.89 | LMNA (0.38) | LMNAMEN1KMT2AGRIN2DGRIN3B | |
| SCHEMBL5812542 | 0.88 | MEN1 (0.54) | LMNAMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL5816185 | 0.88 | MEN1 (0.54) | LMNAMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL5809866 | 0.88 | MEN1 (0.54) | LMNAMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL5306610 | 0.88 | MEN1 (0.54) | LMNAMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL5814804 | 0.88 | MEN1 (0.54) | LMNAMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL5815100 | 0.88 | MEN1 (0.54) | LMNAMEN1KMT2ASIGMAR1ALDH1A1 | |
| SCHEMBL992157 | 0.88 | MEN1 (0.54) | LMNAMEN1KMT2ASIGMAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2493849-B1 | METHOD OF SEPARATION EMPLOYING SWITCHABLE HYDROPHILICITY SOLVENTS | UNIV KINGSTON (CA) | 2021-12-08 | — | — | EP | disclosed |
| US-20150240051-A1 | SWITCHABLE HYDROPHILICITY SOLVENTS AND METHODS OF USE THEREOF | GREENCENTRE CANADA (CA) | 2015-08-27 | — | — | US | disclosed |