Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ESRRB | O95718 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12225818 | 1.00 | TSHR (0.48) | TSHRAKT1POLBESRRBKDM4E | |
| SCHEMBL1702759 | 1.00 | TSHR (0.48) | TSHRAKT1POLBESRRBKDM4E | |
| SCHEMBL6157208 | 0.86 | ALDH1A1 (0.51) | TSHRAKT1POLBESRRBKDM4E | |
| SCHEMBL6157212 | 0.86 | ALDH1A1 (0.51) | TSHRAKT1POLBESRRBKDM4E | |
| SCHEMBL6157204 | 0.86 | ALDH1A1 (0.51) | TSHRAKT1POLBESRRBKDM4E | |
| SCHEMBL1057122 | 0.78 | ATM (0.52) | KDM4EALDH1A1LMNAATMKMT2A | |
| SCHEMBL275775 | 0.76 | KMT2A (0.67) | TSHRAKT1POLBKDM4EALDH1A1 | |
| SCHEMBL8072394 | 0.76 | TSHR (0.56) | TSHRAKT1POLBESRRBKDM4E | |
| SCHEMBL1055554 | 0.75 | SMN1; SMN2 (0.50) | KDM4EALDH1A1ATMKMT2AMAPT | |
| SCHEMBL29035576 | 0.75 | KMT2A (0.64) | TSHRAKT1POLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806408-B1 | Process for producing amino acid derivatives from hydroxyimino acids | AJINOMOTO KK (JP) | 2012-04-18 | — | — | EP | disclosed |
| US-8043836-B2 | Contacting Citrobacter/Escherichia and/or enzyme with a hydroxyimino acid; for biosynthesis of tryptophan | AJINOMOTO CO., INC. (JP) | 2011-10-25 | — | — | US | disclosed |
| US-20080193984-A1 | Process For Producing Amino Acid Derivative From Hydroxyimino Acid | AJINOMOTO CO., INC. (JP) | 2008-08-14 | — | — | US | disclosed |
| EP-1806408-A1 | PROCESS FOR PRODUCING AMINO ACID DERIVATIVE FROM HYDROXYIMINO ACID | Ajinomoto Co., Inc. (JP) | 2007-07-11 | — | — | EP | disclosed |