SCHEMBL17027720

SCHEMBL17027720

CCCCCC/C=C/Cc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 2/20 0.59
MAOB P27338 1/20 0.58
EPHX2 P34913 4/20 0.55
FAAH O00519 3/20 0.55
TOP1 P11387 1/20 0.54
CNR1 P21554 1/20 0.52
CNR2 P34972 1/20 0.52
SOAT2 O75908 1/20 0.50
SOAT1 P35610 1/20 0.50
PPARA Q07869 1/20 0.47
CYP2D6 P10635 1/20 0.47
TRPV1 Q8NER1 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17027721 1.00 KCNH2 (0.59) KCNH2MAOBEPHX2FAAHTOP1
SCHEMBL30610810 1.00 KCNH2 (0.59) KCNH2MAOBEPHX2FAAHTOP1
SCHEMBL19031852 1.00 KCNH2 (0.59) KCNH2MAOBEPHX2FAAHTOP1
SCHEMBL11896271 1.00 KCNH2 (0.59) KCNH2MAOBEPHX2FAAHTOP1
SCHEMBL19031851 1.00 KCNH2 (0.59) KCNH2MAOBEPHX2FAAHTOP1
SCHEMBL19031836 0.98 MAOB (0.60) KCNH2MAOBEPHX2FAAHTOP1
SCHEMBL19031835 0.98 MAOB (0.60) KCNH2MAOBEPHX2FAAHTOP1
SCHEMBL9955098 0.96 TOP1 (0.59) KCNH2MAOBEPHX2FAAHTOP1
SCHEMBL20421295 0.96 TOP1 (0.59) KCNH2MAOBEPHX2FAAHTOP1
SCHEMBL9955102 0.96 TOP1 (0.59) KCNH2MAOBEPHX2FAAHTOP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724729-B 1-Aryl-alpha, beta-unsaturated ketone compound, synthesis method thereof and application thereof in preparation of root-knot nematode killing drugs 陕西省生物农业研究所 2024-05-17 CN claimed
WO-2017111702-A9 DURABLE SUPERHYDROPHOBIC COATING AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2018-07-19 WO disclosed
WO-2017111702-A1 DURABLE SUPERHYDROPHOBIC COATING AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2017-06-29 WO disclosed
WO-2015126462-A1 PREPARATION OF SURFACTANTS VIA CROSS-METATHESIS MATERIA, INC. (US) 2015-08-27 WO disclosed