Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 3/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.51 |
| ▸ | FAAH | O00519 | 2/20 | 0.51 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 1/20 | 0.49 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.46 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20421295 | 1.00 | TOP1 (0.59) | TOP1MAOBKCNH2EPHX2FAAH | |
| SCHEMBL9955102 | 1.00 | TOP1 (0.59) | TOP1MAOBKCNH2EPHX2FAAH | |
| SCHEMBL19031835 | 0.98 | MAOB (0.60) | TOP1MAOBKCNH2EPHX2FAAH | |
| SCHEMBL19031836 | 0.98 | MAOB (0.60) | TOP1MAOBKCNH2EPHX2FAAH | |
| SCHEMBL19031851 | 0.96 | KCNH2 (0.59) | TOP1MAOBKCNH2EPHX2FAAH | |
| SCHEMBL17027721 | 0.96 | KCNH2 (0.59) | TOP1MAOBKCNH2EPHX2FAAH | |
| SCHEMBL30610810 | 0.96 | KCNH2 (0.59) | TOP1MAOBKCNH2EPHX2FAAH | |
| SCHEMBL17027720 | 0.96 | KCNH2 (0.59) | TOP1MAOBKCNH2EPHX2FAAH | |
| SCHEMBL19031852 | 0.96 | KCNH2 (0.59) | TOP1MAOBKCNH2EPHX2FAAH | |
| SCHEMBL11896271 | 0.96 | KCNH2 (0.59) | TOP1MAOBKCNH2EPHX2FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655307-B1 | COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS | GIVAUDAN SA (CH) | 2018-08-01 | — | — | EP | claimed |
| EP-2655307-A1 | COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS | Givaudan SA (CH) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012085287-A1 | COMPOUNDS CAPABLE OF RELEASING FRAGRANT COMPOUNDS | GIVAUDAN SA (CH) | 2012-06-28 | — | — | WO | disclosed |