SCHEMBL17027769

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1337675	0.81	DHODH (0.49)	DHODHFFAR4IGF1RSLC6A2SLC6A4
	SCHEMBL1337890	0.80	DHODH (0.46)	DHODHFFAR4SLC6A2SLC6A4SLC6A3
	SCHEMBL17027815	0.79	MAP4K4 (0.59)	DHODHMAP4K4IGF1RSLC6A2SLC6A4
	SCHEMBL2595252	0.78	SLC6A2 (0.55)	DHODHFFAR4SLC6A2SLC6A4SLC6A3
	SCHEMBL30693953	0.77	FYN (0.51)	DHODHFYNMAP4K4CHEK2
	SCHEMBL1336643	0.76	FFAR4 (0.51)	DHODHFFAR4IGF1RSLC6A2SLC6A4
	SCHEMBL17027843	0.76	JAK2 (0.48)	DHODHFYNMAP4K4CHEK2
	SCHEMBL1337871	0.75	SLC6A2 (0.50)	DHODHFFAR4IGF1RSLC6A2SLC6A4
	SCHEMBL16334746	0.73	FFAR4 (0.56)	DHODHFFAR4IGF1RSLC6A2SLC6A4
	SCHEMBL20000562	0.72	PDGFRB (0.44)	ALOX5APFEN1CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.