Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.55 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | DHODH | Q02127 | 3/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7235082 | 0.89 | SLC6A2 (0.67) | SLC6A2SLC6A3SLC6A4SMN1; SMN2 | |
| SCHEMBL28054784 | 0.85 | SLC6A2 (0.49) | SLC6A2SLC6A3SLC6A4ENPP2DHODH | |
| SCHEMBL1075662 | 0.83 | SLC6A4 (0.83) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL1075663 | 0.83 | SLC6A4 (0.83) | SLC6A2SLC6A3SLC6A4 | |
| SCHEMBL23099877 | 0.81 | SLC6A2 (0.63) | SLC6A2SLC6A3SLC6A4SMN1; SMN2 | |
| SCHEMBL18997019 | 0.81 | SLC6A2 (0.63) | SLC6A2SLC6A3SLC6A4FFAR4SMN1; SMN2 | |
| SCHEMBL16569940 | 0.81 | SLC6A2 (0.58) | SLC6A2SLC6A3SLC6A4SMN1; SMN2 | |
| SCHEMBL18186076 | 0.81 | SLC6A2 (0.58) | SLC6A2SLC6A3SLC6A4SMN1; SMN2 | |
| SCHEMBL1337675 | 0.80 | DHODH (0.49) | SLC6A2SLC6A3SLC6A4ENPP2DHODH | |
| SCHEMBL1337890 | 0.79 | DHODH (0.46) | SLC6A2SLC6A3SLC6A4TAAR1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2566847-A1 | NOVEL IMMUNOMODULATOR AND ANTI INFLAMMATORY COMPOUNDS | Icozen Therapeutics Pvt. Ltd. (IN) | 2013-03-13 | — | — | EP | disclosed |
| WO-2011138665-A1 | NOVEL IMMUNOMODULATOR AND ANTI INFLAMMATORY COMPOUNDS | INCOZEN THERAPEUTICS PVT. LTD. (IN) | 2011-11-10 | — | — | WO | disclosed |