SCHEMBL17027804

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29568613	0.92	MAP4K4 (0.64)	MAP4K4PIK3CDBACE1MKNK1MKNK2
	SCHEMBL68829	0.92	MAP4K4 (0.64)	MAP4K4PIK3CDBACE1MKNK1MKNK2
	SCHEMBL20704158	0.90	MAP4K4 (0.62)	MAP4K4PIK3CDBACE1MKNK1MKNK2
	SCHEMBL30337416	0.82	PIK3CD (0.70)	MAP4K4PIK3CDMKNK1MKNK2DYRK1A
	SCHEMBL1477226	0.82	MAP4K4 (0.70)	MAP4K4PIK3CDDYRK1ADYRK1B
	SCHEMBL12349144	0.81	MAP4K4 (0.68)	MAP4K4PIK3CDMKNK1MKNK2DYRK1A
	SCHEMBL2319381	0.81	MAP4K4 (0.68)	MAP4K4PIK3CDBACE1DYRK1ADYRK1B
	SCHEMBL1257460	0.80	PIK3CD (0.73)	MAP4K4PIK3CDMKNK1MKNK2DYRK1A
	SCHEMBL29740321	0.80	PIK3CD (0.73)	MAP4K4PIK3CDMKNK1MKNK2DYRK1A
	SCHEMBL21190373	0.78	PIK3CD (0.50)	MAP4K4PIK3CDMKNK1MKNK2ALK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.