Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28880428 | 0.84 | TSHR (0.69) | MAPTKDM4EGAACYP2C19TSHR | |
| SCHEMBL12672579 | 0.84 | HDAC1 (0.70) | MAPTKDM4EGAACYP2C19TSHR | |
| SCHEMBL7530630 | 0.83 | MAPT (0.66) | MAPTKDM4EGAACYP2C19TSHR | |
| SCHEMBL6293462 | 0.82 | MAPT (0.70) | MAPTKDM4EGAACYP2C19TSHR | |
| SCHEMBL6290020 | 0.82 | MAPT (0.70) | MAPTKDM4EGAACYP2C19TSHR | |
| SCHEMBL7929898 | 0.81 | MAPT (0.68) | MAPTKDM4EGAACYP2C19TSHR | |
| SCHEMBL17501853 | 0.81 | KDM4E (0.68) | MAPTKDM4EGAACYP2C19TSHR | |
| SCHEMBL4867099 | 0.81 | MAPT (0.68) | MAPTKDM4EGAACYP2C19TSHR | |
| SCHEMBL11114287 | 0.81 | MAPT (0.68) | MAPTKDM4EGAACYP2C19TSHR | |
| SCHEMBL8144840 | 0.81 | MAPT (0.68) | MAPTKDM4EGAACYP2C19TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126930-A2 | BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS | STC.UNM (US) | 2015-08-27 | — | — | WO | claimed |