Sugi Predict

Sugi Predict / Compounds / SCHEMBL7530630

SCHEMBL7530630

SCHEMBL7530630

CC(=O)CC(=O)Nc1cccc2ccccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAPT P10636 2/20 0.66
▸ CYP2C19 P33261 3/20 0.63
▸ CYP1A2 P05177 2/20 0.63
▸ KDM4E B2RXH2 4/20 0.61
▸ GAA P10253 1/20 0.61
▸ TSHR P16473 2/20 0.59
▸ ALDH1A1 P00352 3/20 0.58
▸ HPGD P15428 1/20 0.58
▸ USP2 O75604 1/20 0.57
▸ EPHX1 P07099 1/20 0.56
▸ NPC1 O15118 2/20 0.56
▸ RAB9A P51151 2/20 0.56
▸ CYP3A4 P08684 1/20 0.56
▸ CYP2D6 P10635 1/20 0.56
▸ CYP2C9 P11712 1/20 0.56
▸ POLB P06746 2/20 0.55
▸ GSK3B P49841 1/20 0.54
▸ SMN1; SMN2 Q16637 1/20 0.54
▸ CA12 O43570 1/20 0.54
▸ CA4 P22748 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11434479 0.89 ALDH1A1 (0.59) MAPTCYP2C19CYP1A2KDM4EGAA
SCHEMBL17501853 0.84 KDM4E (0.68) MAPTCYP2C19CYP1A2KDM4EGAA
SCHEMBL28880428 0.84 TSHR (0.69) MAPTCYP2C19CYP1A2KDM4EGAA
SCHEMBL30668538 0.84 MAPT (0.68) MAPTCYP2C19CYP1A2KDM4EGAA
SCHEMBL1285414 0.84 MAPT (0.68) MAPTCYP2C19CYP1A2KDM4EGAA
SCHEMBL29949051 0.83 CYP2C19 (0.78) MAPTCYP2C19CYP1A2KDM4EGAA
SCHEMBL2912340 0.83 MAPT (0.58) MAPTCYP2C19CYP1A2KDM4ETSHR
SCHEMBL12456328 0.83 CYP2C19 (0.72) MAPTCYP2C19CYP1A2KDM4EGAA
SCHEMBL12608238 0.83 CYP2C19 (0.72) MAPTCYP2C19CYP1A2KDM4EGAA
SCHEMBL17028010 0.83 MAPT (0.66) MAPTCYP2C19CYP1A2KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3122820-B1 STORAGE-STABLE DYE SOLUTIONS ARCHROMA IP GMBH (CH) 2019-03-13 — — EP claimed
CN-106459600-A Storage-stable dye solutions 昂高知识产权有限公司 2017-02-22 — — CN claimed
US-20170022366-A1 STORAGE-STABLE DYE SOLUTIONS ARCHROMA IP GMBH (CH) 2017-01-26 — — US claimed
EP-0079563-B1 WATER SOLUBLE 1:2 METAL COMPLEX AZO COMPOUNDS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1986-01-08 — — EP claimed
EP-0071168-B1 WATER-SOLUBLE DISAZO COMPOUNDS AND BIS-(AMINO-PHENOXY)-ETHANE COMPOUNDS WITH FIBRE REACTIVE GROUPS AS TETRAZO COMPOUNDS, PROCESS FOR THE PREPARATION OF THESE COMPOUNDS AND THE USE OF THE DISAZO COMPOUNDS AS DYESTUFFS HOECHST AKTIENGESELLSCHAFT (DE) 1985-01-30 — — EP claimed
EP-0079563-A2 Water soluble 1:2 metal complex azo compounds, process for their preparation and their use as dyestuffs HOECHST AKTIENGESELLSCHAFT (DE) 1983-05-25 — — EP claimed
CN-115093341-B 2-cyclopentene-1-alcohol derivative and synthetic method and application thereof 江西省科学院应用化学研究所 2024-03-08 — — CN disclosed
CN-116829137-A Pharmaceutical compositions of naphthalene derivatives as multi-target therapeutic agents for the treatment of Alzheimer's disease 古巴神经科学中心 2023-09-29 — — CN disclosed
EP-3303353-B1 PROCESS JOHNSON MATTHEY PLC (GB) 2022-01-12 — — EP disclosed
EP-3303353-B1 PROCESS JOHNSON MATTHEY PLC (GB) 2022-01-12 — — EP disclosed
EP-3561003-A1 A HYBRID PIGMENT, METHOD FOR PREPARATION THEREOF AND USES THEREOF Clariant Plastics & Coatings Ltd (CH) 2019-10-30 — — EP disclosed
US-10428098-B2 Processes for preparing and using ruthenium and osmium complexes JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2019-10-01 — — US disclosed
US-10428098-B2 Processes for preparing and using ruthenium and osmium complexes JOHNSON MATTHEY PUBLIC LIMITED COMPANY (GB) 2019-10-01 — — US disclosed
US-4296028-A Pyrazolonyl substituted disazo pigments BASF ITALIA SPA (IT) 1981-10-20 — — US disclosed
US-4269769-A Diazo compounds obtained by coupling acetoacetanilides with tetrazotized diaminobenzanilides AZIENDE COLORI NAZIONALI AFFINI ACNA S.P.A. (IT) 1981-05-26 — — US disclosed
EP-0029009-A1 Preparation of pigments CIBA-GEIGY AG (CH) 1981-05-20 — — EP disclosed
US-4228071-A Triazine containing fiber-reactive disazo dyestuffs CIBA-GEIGY CORPORATION (US) 1980-10-14 — — US disclosed
US-4225492-A Water-soluble disazo dyestuffs, prepared from unsymmetrical heterocyclic diamines CASSELLA AKTIENGESELLSCHAFT (DE) 1980-09-30 — — US disclosed
US-4169091-A Symmetrical and asymmetrical disazo compounds containing a bis-(nitro-aryloxy)alkane middle component HOECHST AKTIENGESELLSCHAFT (DE) 1979-09-25 — — US disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10428098-B2 Processes for preparing and using ruthenium and osmium complexes OSTC, OTC, ORC3 MAPT 3267/4885CYP2C19 3274/4885CYP1A2 1029/4885
US-20170022366-A1 STORAGE-STABLE DYE SOLUTIONS IK, G6PD, TYR MAPT 230/4885CYP2C19 336/4885CYP1A2 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.