Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30879612 | 0.84 | MEN1 (0.59) | KMT2AMEN1HSD17B10NAPRTNPC1 | |
| SCHEMBL8517158 | 0.74 | HSD17B10 (0.77) | KMT2AMEN1HSD17B10NAPRTNPC1 | |
| SCHEMBL2512409 | 0.73 | MLYCD (0.65) | KMT2AMEN1HSD17B10NAPRTNPC1 | |
| SCHEMBL10791571 | 0.72 | MEN1 (0.59) | KMT2AMEN1HSD17B10NAPRTNPC1 | |
| SCHEMBL7613102 | 0.72 | MTOR (0.58) | KMT2AMEN1HSD17B10NAPRTNPC1 | |
| SCHEMBL1382899 | 0.72 | MEN1 (0.67) | KMT2AMEN1HSD17B10NAPRTNPC1 | |
| SCHEMBL11231678 | 0.72 | HSD17B10 (0.55) | KMT2AMEN1HSD17B10NAPRTNPC1 | |
| SCHEMBL27342484 | 0.71 | NPSR1 (0.50) | KMT2AMEN1HSD17B10NAPRTNPC1 | |
| SCHEMBL5974531 | 0.71 | MAPT (0.58) | KMT2AMEN1HSD17B10NAPRTNPC1 | |
| SCHEMBL5974527 | 0.71 | MAPT (0.58) | KMT2AMEN1NPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015126930-A2 | BOOSTER DRUG THERAPY FOR MYCOBACTERIUM INFECTIONS | STC.UNM (US) | 2015-08-27 | — | — | WO | claimed |