Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17007140 | 1.00 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL17007266 | 0.87 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL17007385 | 0.86 | HCRTR1 (0.51) | HCRTR1HCRTR2 | |
| SCHEMBL17007313 | 0.86 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL17007246 | 0.85 | HCRTR1 (0.64) | HCRTR1HCRTR2 | |
| SCHEMBL17007221 | 0.83 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL17166533 | 0.83 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL22877019 | 0.83 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL17017337 | 0.82 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL17028043 | 0.80 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107898-A1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2016-12-28 | — | — | EP | disclosed |
| WO-2015124932-A1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | TAKEDA CAMBRIDGE LIMITED (GB) | 2015-08-27 | — | — | WO | disclosed |