Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 16/20 | 0.54 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.39 |
| ▸ | LATS1 | O95835 | 3/20 | 0.39 |
| ▸ | LATS2 | Q9NRM7 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17166533 | 0.86 | HCRTR1 (0.54) | HCRTR1HCRTR2 | |
| SCHEMBL17166360 | 0.85 | HCRTR1 (0.41) | HCRTR1HCRTR2LATS1LATS2 | |
| SCHEMBL17017337 | 0.85 | HCRTR1 (0.53) | HCRTR1HCRTR2 | |
| SCHEMBL17028066 | 0.83 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL17007140 | 0.83 | HCRTR1 (0.65) | HCRTR1HCRTR2 | |
| SCHEMBL22877014 | 0.80 | GABBR2 (0.49) | HCRTR1 | |
| SCHEMBL17007313 | 0.80 | HCRTR1 (0.59) | HCRTR1HCRTR2 | |
| SCHEMBL17007306 | 0.72 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL17028043 | 0.72 | HCRTR1 (1.00) | HCRTR1HCRTR2 | |
| SCHEMBL17007202 | 0.72 | HCRTR1 (1.00) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107898-B1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-01-06 | — | — | EP | disclosed |