Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28108713 | 0.75 | GAA (0.36) | GAAHPGDMAPK1 | |
| SCHEMBL2163195 | 0.73 | GAA (0.37) | GAAHPGDMAPK1 | |
| SCHEMBL8524485 | 0.72 | GAA (0.39) | GAAHPGDMAPK1 | |
| SCHEMBL1908027 | 0.70 | GAA (0.44) | GAAHPGDMAPK1 | |
| SCHEMBL9663054 | 0.70 | GAA (0.36) | GAAHPGDMAPK1 | |
| SCHEMBL30751 | 0.68 | GAA (0.43) | GAAHPGDMAPK1 | |
| SCHEMBL486158 | 0.67 | GAA (0.45) | GAAHPGDMAPK1 | |
| Hydrochloric Acid SCHEMBL2957423 | 0.67 | GAA (0.42) | GAAHPGDMAPK1 | |
| SCHEMBL17028086 | 0.66 | — | — | |
| SCHEMBL28710587 | 0.64 | GAA (0.46) | GAAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107898-B1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | TAKEDA PHARMACEUTICALS CO (JP) | 2021-01-06 | — | — | EP | disclosed |
| EP-3107898-A1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | Takeda Pharmaceutical Company Limited (JP) | 2016-12-28 | — | — | EP | disclosed |
| US-9493432-B2 | Cyclopentylbenzamide derivatives and their use for the treatment of psychotic and cognitive disorders | TAKEDA PHARMACEUTICALS COMPANY LIMITED (JP) | 2016-11-15 | — | — | US | disclosed |
| WO-2015124932-A1 | 1,2-SUBSTITUTED CYCLOPENTANES AS OREXIN RECEPTOR ANTAGONISTS | TAKEDA CAMBRIDGE LIMITED (GB) | 2015-08-27 | — | — | WO | disclosed |