Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NOS1 | P29475 | 4/20 | 0.32 |
| ▸ | NOS2 | P35228 | 4/20 | 0.32 |
| ▸ | NOS3 | P29474 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL2957423 | 0.98 | GAA (0.42) | GAAHPGDMAPK1MAPTNOS1 | |
| SCHEMBL2163195 | 0.94 | GAA (0.37) | GAAHPGDMAPK1MAPT | |
| SCHEMBL10607707 | 0.85 | GAA (0.33) | GAAHPGDMAPK1 | |
| SCHEMBL28710587 | 0.79 | GAA (0.46) | GAAHPGDMAPK1MAPTNOS1 | |
| SCHEMBL3372805 | 0.77 | NOS3 (0.30) | NOS1NOS2NOS3 | |
| SCHEMBL486158 | 0.77 | GAA (0.45) | GAAHPGDMAPK1MAPTNOS1 | |
| SCHEMBL9306327 | 0.74 | GAA (0.43) | GAAHPGDMAPK1MAPT | |
| SCHEMBL9663054 | 0.73 | GAA (0.36) | GAAHPGDMAPK1 | |
| SCHEMBL29035855 | 0.73 | GAA (0.42) | GAAHPGDMAPK1MAPT | |
| SCHEMBL20912807 | 0.71 | GAA (0.35) | GAAHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1265888-B1 | METHOD OF PRODUCING 6-SUBSTITUTED ( S )-NICOTINE DERIVATIVES AND INTERMEDIATE COMPOUNDS | INDEPENDENT PHARMACEUTICA AB (SE) | 2004-08-11 | — | — | EP | claimed |
| US-6747156-B2 | Method of producing 6-substituted (s)-nicotine derivatives and intermediate compounds | INDEPENDENT PHARMACEUTICA AB (SE) | 2004-06-08 | — | — | US | claimed |
| US-20030187270-A1 | Method of producing 6-substituted (s)-Nicotine derivatives and intermediate compounds | INDEPENDENT PHARMACEUTICA AB (SE) | 2003-10-02 | — | — | US | claimed |
| EP-1265888-A1 | METHOD OF PRODUCING 6-SUBSTITUTED ( i S /i )-NICOTINE DERIVATIVES AND INTERMEDIATE COMPOUNDS | Independent pharmaceutica AB (SE) | 2002-12-18 | — | — | EP | claimed |
| WO-2001070730-A1 | METHOD OF PRODUCING 6-SUBSTITUTED (S)-NICOTINE DERIVATIVES AND INTERMEDIATE COMPOUNDS | INDEPENDENT PHARMACEUTICA AB (SE) | 2001-09-27 | — | — | WO | claimed |
| EP-0935624-A1 | RIGID POLYURETHANE FOAMS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1999-08-18 | — | — | EP | claimed |
| WO-1998020058-A1 | RIGID POLYURETHANE FOAMS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1998-05-14 | — | — | WO | claimed |
| US-4942179-A | ISOTROPIC OR ANISOTROPIC FORMULATION AND FLUOROPHOSPHATE SURFACTANTS | ENIRICHERCHE S.P.A. (IT) | 1990-07-17 | — | — | US | claimed |
| EP-0154669-A1 | Catalyst for urethane foam blown with carboxylic acids | ABBOTT LABORATORIES (US) | 1985-09-18 | — | — | EP | claimed |
| US-4473666-A | A DIALKYLCYCLOHEXYLAMINE AND AN N-SUBSTITUTED ALKOXYALKYL PIPERAZINE | ABBOTT LABORATORIES (US) | 1984-09-25 | — | — | US | claimed |
| US-4219624-A | Stabilization of amine catalysts in a composition with halogenated polyols for use in polyurethane foam production | OLIN CORPORATION (US) | 1980-08-26 | — | — | US | claimed |
| US-3992366-A | FOR CROSSLINKING PHOTOGRAPHIC GELATINS | CIBA-GEIGY AG (CH) | 1976-11-16 | — | — | US | claimed |
| US-3980579-A | FOR PREPARATION OF POLYURETHANE FOAMS; TERTIARY AMINE, SULFUR-CONTAINING ORGANOTIN COMPOUND | OLIN CORPORATION (US) | 1976-09-14 | — | — | US | claimed |
| CN-105132209-B | Azeotrope-like compositions comprising the chloro- 3,3,3- trifluoro propene of 1- | 霍尼韦尔国际公司 | 2019-11-26 | — | — | CN | disclosed |
| CN-108263050-B | A kind of polyurethane composite sound isolating material and preparation method thereof and power device | 比亚迪股份有限公司 | 2019-11-05 | — | — | CN | disclosed |
| EP-3184171-B1 | PHOSPHINYL AMIDINE COMPOUNDS, METAL COMPLEXES, CATALYST SYSTEMS, AND THEIR USE TO OLIGOMERIZE OR POLYMERIZE OLEFINS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2019-03-20 | — | — | EP | disclosed |
| EP-0013759-A2 | N-sulfenyldiurethanes, process for their preparation and herbicides containing them as active substances | BASF Aktiengesellschaft (DE) | 1980-08-06 | — | — | EP | disclosed |
| US-4098810-A | FUNGICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | disclosed |
| US-3992366-A | FOR CROSSLINKING PHOTOGRAPHIC GELATINS | CIBA-GEIGY AG (CH) | 1976-11-16 | — | — | US | disclosed |
| US-3980579-A | FOR PREPARATION OF POLYURETHANE FOAMS; TERTIARY AMINE, SULFUR-CONTAINING ORGANOTIN COMPOUND | OLIN CORPORATION (US) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030187270-A1 | Method of producing 6-substituted (s)-Nicotine derivatives and intermediate compounds | SMOX, SLC1A5, SLC43A1 | GAA 3694/4885HPGD 629/4885MAPK1 3960/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.