Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 14/20 | 0.40 |
| ▸ | HTR1A | P08908 | 13/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 12/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 10/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145685 | 0.69 | TDP1 (0.41) | TDP1ADRA1AHTR1AADRA1DADRA1B | |
| SCHEMBL1583161 | 0.67 | TDP1 (1.00) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL1582872 | 0.67 | TDP1 (1.00) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL17028904 | 0.67 | TDP1 (1.00) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL31220 | 0.67 | TDP1 (1.00) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL246844 | 0.67 | TDP1 (0.54) | TDP1ADRA1AHTR1AADRA1DADRA1B | |
| Methane SCHEMBL11454420 | 0.66 | TDP1 (0.96) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| SCHEMBL21178023 | 0.66 | TDP1 (0.96) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| Water SCHEMBL6248999 | 0.66 | TDP1 (0.96) | TDP1ALDH1A1TP53CYP3A4TSHR | |
| Iodide SCHEMBL9053819 | 0.66 | TDP1 (0.96) | TDP1ALDH1A1TP53CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107521-A1 | ADHESIVE BONDING COMPOSITION AND USE THEREOF | 3M Innovative Properties Company (US) | 2016-12-28 | — | — | EP | disclosed |
| EP-3107523-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M Innovative Properties Company (US) | 2016-12-28 | — | — | EP | disclosed |
| WO-2015126865-A1 | ADHESIVE BONDING COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |
| WO-2015126862-A1 | DENTAL COMPOSITION AND USE THEREOF | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2015-08-27 | — | — | WO | disclosed |