SCHEMBL246844

SCHEMBL246844

c1ccc(OCC2(CC3CO3)CO2)cc1

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.54
ADRA1A P35348 10/20 0.41
HTR1A P08908 9/20 0.41
ADRA1D P25100 7/20 0.41
ADRA1B P35368 6/20 0.41
ALDH1A1 P00352 2/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
TSHR P16473 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HIF1A Q16665 1/20 0.41
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
GLA P06280 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3480269 0.83 TDP1 (0.36) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL7269669 0.82 KCNA3 (0.44) TDP1ADRA1AHTR1AALDH1A1
SCHEMBL1352539 0.78 ALDH1A1 (0.38) TDP1ADRA1AHTR1AADRA1DADRA1B
SCHEMBL4451944 0.76 LTA4H (0.41) TDP1HTR1AALDH1A1
SCHEMBL27760167 0.76 TAAR1 (0.44) TDP1ALDH1A1
SCHEMBL476346 0.75 TDP1 (0.38) TDP1ADRA1AHTR1AALDH1A1SMN1; SMN2
SCHEMBL7218155 0.72 THRB (0.38) TDP1ADRA1AHTR1AADRA1DADRA1B
SCHEMBL1583161 0.71 TDP1 (1.00) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL17028904 0.71 TDP1 (1.00) TDP1ALDH1A1TP53CYP3A4TSHR
SCHEMBL1582872 0.71 TDP1 (1.00) TDP1ALDH1A1TP53CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110869454-A Solid homogeneous amorphous high-heat epoxy resin blend, product and application thereof 沙特基础工业全球技术有限公司 2020-03-06 CN claimed
CN-104031396-B A kind of cold mixing epoxy bitumen material and preparation method thereof 湖北大学 2019-08-30 CN claimed
EP-0262891-B1 Resin composition of thermosetting resin and thermoplastic resin TOHO RAYON KK (JP) 1996-12-27 EP claimed
EP-0262891-A2 Resin composition of thermosetting resin and thermoplastic resin Toho Rayon Co., Ltd. (JP) 1988-04-06 EP claimed
CN-116987233-A Cationic UV (ultraviolet) heat curing composition and preparation method thereof 上海汉司实业有限公司 2023-11-03 CN disclosed
CN-116113673-A Low reflectivity dual cure adhesive composition 汉高股份有限及两合公司 2023-05-12 CN disclosed
US-20230119661-A1 METHOD FOR PRODUCING A LAMINATION STACK, LAMINATION STACK AND ELECTRIC MACHINE THYSSENKRUPP STEEL EUROPE AG (DE) 2023-04-20 US disclosed
US-20220220593-A1 SHEET METAL FOR PRODUCING AN ELECTROMAGNETIC COMPONENT, IN PARTICULAR A STATOR CORE OR ROTOR CORE, AND METHOD FOR PRODUCING AN ELECTROMAGNETIC COMPONENT THYSSENKRUPP STEEL EUROPE AG (DE) 2022-07-14 US disclosed
EP-3724253-B1 LIGHT-FIXABLE AND HEAT-CURING COMPOUNDS BASED ON EPOXY RESINS AND THIOLS DELO INDUSTRIE KLEBSTOFFE GMBH & CO KGAA (DE) 2022-01-05 EP disclosed
EP-3724253-A1 LIGHT-FIXABLE AND HEAT-CURING COMPOUNDS BASED ON EPOXY RESINS AND THIOLS DELO Industrie Klebstoffe GmbH & Co. KGaA (DE) 2020-10-21 EP disclosed
EP-3707216-A1 METHOD FOR PRODUCING OPAQUE COATINGS, ADHESIVE BONDS AND CASTINGS, AND A CURABLE COMPOUND FOR USE IN THE METHOD DELO Industrie Klebstoffe GmbH & Co. KGaA (DE) 2020-09-16 EP disclosed
CN-108424698-B Method for forming multilayer coating film 关西涂料株式会社 2020-08-04 CN disclosed
EP-1050346-A1 METHOD OF FORMING MULTILAYERED TOPCOAT FILM KANSAI PAINT CO., LTD. (JP) 2000-11-08 EP disclosed
US-6136921-A ALKALI METAL-TERMINATED POLYMER REACTED WITH DIGLYCIDYL ETHER DERIVATIVE COUPLING AGENT; CORROSION AND WEAR RESISTANCE; RADIATION TRANSPARENT TAIWAN SYNTHETIC RUBBER CORPERATION (TW) 2000-10-24 US disclosed
US-5609918-A CLEAR, RESIN WITH A HYDROXY GROUP AND AN EPOXY GROUP, REACTION WITH A SILICON COMPOUND KANSAI PAINT COMPANY LIMITED (JP) 1997-03-11 US disclosed
EP-0262891-B1 Resin composition of thermosetting resin and thermoplastic resin TOHO RAYON KK (JP) 1996-12-27 EP disclosed
US-4962162-A TOUGHNESS, IMPACT AND COMPRESSIVE STRENGTH TOHO RAYON CO., LTD. (JP) 1990-10-09 US disclosed
EP-0358238-A2 Resin compositions and a method of curing the same KANSAI PAINT CO., LTD. (JP) 1990-03-14 EP disclosed
US-4829124-A BLEND OF CARBOXYLATED ACRYLONITRILE-BURTADIENE COPOLYMER, NEUTRALIZED ETHYLENE-ACRYLIC ACID COPOLYMER AND EPXOY CROSSLINKING AGENT ARMSTRONG WORLD INDUSTRIES, INC. (US) 1989-05-09 US disclosed
EP-0262891-A2 Resin composition of thermosetting resin and thermoplastic resin Toho Rayon Co., Ltd. (JP) 1988-04-06 EP disclosed