Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 3/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.41 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.41 |
| ▸ | VCP | P55072 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2751689 | 0.81 | TSHR (0.33) | TSHR | |
| SCHEMBL9955989 | 0.79 | NR4A1 (0.41) | TP53IDO1NOTUMGABRPGABRD | |
| SCHEMBL17028922 | 0.77 | NOTUM (0.47) | TDO2NPC1RAB9ANOTUMVCP | |
| SCHEMBL500129 | 0.77 | ALOX15 (0.41) | SMN1; SMN2NPC1TSHRNFKB1RAB9A | |
| SCHEMBL2752047 | 0.76 | AHR (0.46) | SMN1; SMN2NPC1RAB9ANOTUMDHFR | |
| SCHEMBL17028877 | 0.75 | NOTUM (0.45) | NPC1RAB9AIDO1NOTUMSCN2A | |
| SCHEMBL2752199 | 0.72 | CYP1A2 (0.31) | — | |
| SCHEMBL2752930 | 0.71 | IDO1 (0.41) | SMN1; SMN2TP53TSHRRAB9AIDO1 | |
| SCHEMBL2753580 | 0.71 | ALOX15 (0.41) | SMN1; SMN2NPC1TP53TSHRRAB9A | |
| SCHEMBL2337861 | 0.70 | SOS1 (0.42) | TDO2SMN1; SMN2NPC1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116745289-A | Agonists of free fatty acid receptor 1 and their use in diseases associated with said receptor | 奥洛治疗有限公司 | 2023-09-12 | — | — | CN | disclosed |
| WO-2015124606-A1 | N-SUBSTITUTED IMINO HETEROCYCLIC COMPOUNDS FOR COMBATING INVERTEBRATE PESTS | BASF SE (DE) | 2015-08-27 | — | — | WO | disclosed |