Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 5/20 | 0.48 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13003474 | 0.91 | MTOR (0.41) | MTORGRM5MYCSCN9AMAPT | |
| SCHEMBL1483834 | 0.90 | MTOR (0.43) | MTORGRM5SCN9AMAPTSMN1; SMN2 | |
| SCHEMBL12829637 | 0.90 | MTOR (0.43) | MTORGRM5SCN9AMAPTSMN1; SMN2 | |
| SCHEMBL1483831 | 0.90 | MTOR (0.43) | MTORGRM5SCN9AMAPTSMN1; SMN2 | |
| SCHEMBL1483443 | 0.88 | ALDH1A1 (0.42) | MTORGRM5MYCSCN9AMAPT | |
| SCHEMBL12829594 | 0.88 | ALDH1A1 (0.42) | MTORGRM5MYCSCN9AMAPT | |
| SCHEMBL1483445 | 0.88 | ALDH1A1 (0.42) | MTORGRM5MYCSCN9AMAPT | |
| SCHEMBL12829654 | 0.87 | MTOR (0.46) | MTORGRM5SCN9AMAPTSMN1; SMN2 | |
| SCHEMBL12755600 | 0.87 | GRM5 (0.46) | MTORGRM5MAPTSMN1; SMN2RAB9A | |
| SCHEMBL12755834 | 0.86 | KDM2B (0.40) | MTORGRM5SCN9AMAPTKDM2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115341-B2 | Method for expanding hematopoietic stem cells using heterocyclic compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2015-08-25 | — | — | US | disclosed |