SCHEMBL17029133

SCHEMBL17029133

Cc1cc(N=C=O)cc(O[Si](C)(C)C(C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 4/20 0.35
CA1 P00915 4/20 0.35
CA9 Q16790 4/20 0.35
PREP P48147 2/20 0.34
TRPA1 O75762 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5051918 0.78 CA12 (0.42) CA12CA1CA9PREPCYP3A4
SCHEMBL26763405 0.78 CA12 (0.42) CA12CA1CA9PREPCYP3A4
SCHEMBL7906238 0.78 PREP (0.43) CA12CA1CA9PREPTRPA1
SCHEMBL19219046 0.74 TRPA1 (0.36) TRPA1CYP3A4
SCHEMBL1616252 0.73 CA12 (0.38) CA12CA1CA9PREP
SCHEMBL59852 0.72 CYP3A4 (0.48) TRPA1CYP3A4
SCHEMBL109084 0.72 CYP3A4 (0.48) TRPA1CYP3A4
SCHEMBL4406786 0.72 CA12 (0.38) CA12CA1CA9PREP
SCHEMBL565759 0.70 CA12 (0.37) CA12CA1CA9PREP
SCHEMBL17922585 0.70 CA12 (0.37) CA12CA1CA9PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9115164-B2 Substituted aromatic compound, hydrogelation agent, hydrogel, and method for gelating aqueous sample NATIONAL UNIVERSITY CORPORATION SHIZUOKA UNIVERSITY (JP) 2015-08-25 US disclosed