SCHEMBL17029281

SCHEMBL17029281

CCC(CC(C)O)C(F)(F)F

nearest known ligand 0.43

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21415551 0.84 TSHR (0.38) TSHR
SCHEMBL19669575 0.81 ALDH1A1 (0.32) TSHR
SCHEMBL23902179 0.81 ALDH1A1 (0.32) TSHR
SCHEMBL22821854 0.81
SCHEMBL12040104 0.77 TSHR (0.45) TSHRTDP1
SCHEMBL24445322 0.77
SCHEMBL12040035 0.77 TSHR (0.45) TSHRTDP1
SCHEMBL83145 0.74
SCHEMBL15482023 0.74
SCHEMBL15479603 0.73 ALDH1A1 (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9114198-B2 Biologically beneficial coatings for implantable devices containing fluorinated polymers and methods for fabricating the same ADVANCED CARDIOVASCULAR SYSTEMS, INC. (US) 2015-08-25 US disclosed