Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2733029 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4EHSD11B1TSHR | |
| SCHEMBL410464 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4EHSD11B1TSHR | |
| SCHEMBL1270440 | 0.87 | ALDH1A1 (0.50) | ALDH1A1HSD17B10KDM4EHSD11B1TSHR | |
| Hydrochloric Acid SCHEMBL12465553 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HSD17B10KDM4EHSD11B1TSHR | |
| SCHEMBL25761993 | 0.84 | HSD17B10 (0.41) | ALDH1A1HSD17B10KDM4ETSHRKMT2A | |
| SCHEMBL23568185 | 0.81 | ALDH1A1 (0.46) | ALDH1A1HSD17B10KDM4EHSD11B1TSHR | |
| SCHEMBL23562049 | 0.80 | HSD17B10 (0.41) | ALDH1A1HSD17B10SLC6A9 | |
| SCHEMBL18371474 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HSD17B10KDM4ETSHRKMT2A | |
| SCHEMBL25762336 | 0.79 | CHRM5 (0.41) | HSD17B10SLC6A9 | |
| SCHEMBL25762634 | 0.79 | CHRM5 (0.41) | HSD17B10SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115172-B2 | Methods and compositions for improved F-18 labeling of proteins, peptides and other molecules | IMMUNOMEDICS, INC. (US) | 2015-08-25 | — | — | US | disclosed |