Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17029336 | 0.87 | — | — | |
| SCHEMBL24594989 | 0.74 | GRIK1 (0.33) | GRIK1GRIK2 | |
| SCHEMBL17029324 | 0.74 | GRIK1 (0.33) | GRIK1GRIK2 | |
| SCHEMBL22680713 | 0.73 | NOS2 (0.34) | — | |
| SCHEMBL10425711 | 0.68 | GRIK1 (0.40) | GRIK1GRIK2 | |
| SCHEMBL10425642 | 0.68 | GRIK1 (0.40) | GRIK1GRIK2 | |
| SCHEMBL27415685 | 0.67 | GRIK1 (0.34) | GRIK1GRIK2 | |
| SCHEMBL580203 | 0.66 | GRIK1 (0.55) | GRIK1GRIK2 | |
| SCHEMBL23643977 | 0.66 | GRIK1 (0.33) | GRIK1GRIK2 | |
| SCHEMBL580204 | 0.66 | GRIK1 (0.55) | GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160362421-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | GILEAD SCIENCES, INC. | 2016-12-15 | — | — | US | disclosed |
| US-9403782-B2 | Fused heterocyclic compounds as ion channel modulators | GILEAD SCIENCES, INC. (US) | 2016-08-02 | — | — | US | disclosed |
| US-9115096-B2 | Fused heterocyclic compounds as ion channel modulators | GILEAD SCIENCES, INC. (US) | 2015-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160362421-A1 | FUSED HETEROCYCLIC COMPOUNDS AS ION CHANNEL MODULATORS | KCNJ2, CACNA1A, KCNH2 | GRIK1 333/4885GRIK2 385/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.