Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 2/20 | 0.48 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 6/20 | 0.40 |
| ▸ | CALCRL | Q16602 | 2/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | FAP | Q12884 | 2/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.39 |
| ▸ | PREP | P48147 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.39 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10297448 | 1.00 | XIAP (0.48) | XIAPMLXELANECALCRLDPP4 | |
| SCHEMBL10297419 | 1.00 | XIAP (0.48) | XIAPMLXELANECALCRLDPP4 | |
| SCHEMBL10297449 | 0.89 | XIAP (0.49) | XIAPMLXELANECALCRLTAAR1 | |
| SCHEMBL10297437 | 0.89 | XIAP (0.49) | XIAPMLXELANECALCRLTAAR1 | |
| SCHEMBL29697762 | 0.87 | XIAP (0.51) | XIAPMLXELANECALCRLTAAR1 | |
| SCHEMBL10297469 | 0.85 | XIAP (0.43) | XIAP | |
| SCHEMBL10297432 | 0.85 | XIAP (0.43) | XIAP | |
| SCHEMBL17029373 | 0.84 | CMA1 (0.49) | ELANE | |
| SCHEMBL10297454 | 0.84 | CMA1 (0.49) | ELANE | |
| SCHEMBL10297416 | 0.84 | CMA1 (0.49) | ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9114104-B2 | Proteinase K inhibitors, methods and compositions therefor | Life Technologies Corporation (US) | 2015-08-25 | — | — | US | disclosed |