Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XIAP | P98170 | 3/20 | 0.51 |
| ▸ | ELANE | P08246 | 11/20 | 0.41 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | CALCRL | Q16602 | 1/20 | 0.37 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10297437 | 0.98 | XIAP (0.49) | XIAPELANEMLXCMA1TAAR1 | |
| SCHEMBL10297449 | 0.98 | XIAP (0.49) | XIAPELANEMLXCMA1TAAR1 | |
| SCHEMBL5925735 | 0.89 | XIAP (0.47) | XIAPELANEMLXCMA1TAAR1 | |
| SCHEMBL17029370 | 0.87 | XIAP (0.48) | XIAPELANEMLXTAAR1CALCRL | |
| SCHEMBL10297448 | 0.87 | XIAP (0.48) | XIAPELANEMLXTAAR1CALCRL | |
| SCHEMBL10297419 | 0.87 | XIAP (0.48) | XIAPELANEMLXTAAR1CALCRL | |
| SCHEMBL8920341 | 0.86 | XIAP (0.57) | XIAPELANEMLXCMA1 | |
| SCHEMBL8613939 | 0.86 | XIAP (0.57) | XIAPELANEMLXCMA1 | |
| SCHEMBL770146 | 0.85 | XIAP (0.46) | XIAPELANEMLXCMA1CALCRL | |
| SCHEMBL30216494 | 0.84 | XIAP (0.53) | XIAPELANEMLXCMA1CALCRL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11872261-B2 | Lipoprotein targeting protease inhibitors and uses | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-01-16 | — | — | US | claimed |
| EP-3353316-B1 | METHODS OF PREDICTION OF WOUND HEALING | WOUNDCHEK LABORATORIES INC (US) | 2024-01-10 | — | — | EP | claimed |
| US-20230201298-A1 | LIPOPROTEIN TARGETING PROTEASE INHIBITORS AND USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-06-29 | — | — | US | claimed |
| US-20220168379-A1 | LIPOPROTEIN TARGETING PROTEASE INHIBITORS AND USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2022-06-02 | — | — | US | claimed |
| US-11872261-B2 | Lipoprotein targeting protease inhibitors and uses | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2024-01-16 | — | — | US | disclosed |
| US-20230201298-A1 | LIPOPROTEIN TARGETING PROTEASE INHIBITORS AND USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2023-06-29 | — | — | US | disclosed |
| US-20220168379-A1 | LIPOPROTEIN TARGETING PROTEASE INHIBITORS AND USES | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2022-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11872261-B2 | Lipoprotein targeting protease inhibitors and uses | SERPINB1, APOB, APOL1 | XIAP 1117/4885ELANE 118/4885MLX 963/4885 |
| US-20230201298-A1 | LIPOPROTEIN TARGETING PROTEASE INHIBITORS AND USES | HPN, SERPINB1, PEPD | XIAP 959/4885ELANE 121/4885MLX 704/4885 |
| US-20220168379-A1 | LIPOPROTEIN TARGETING PROTEASE INHIBITORS AND USES | SERPINB1, APOB, APOL1 | XIAP 1117/4885ELANE 118/4885MLX 963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.