SCHEMBL1702939

SCHEMBL1702939

COC(=Cc1ccccc1)C(=O)OC12CCC(CC1)C2

nearest known ligand 0.44

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ABCG2 Q9UNQ0 1/20 0.39
KMT2A Q03164 2/20 0.35
MEN1 O00255 1/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.35
POLB P06746 1/20 0.35
HTT P42858 1/20 0.35
RAB9A P51151 2/20 0.33
NPC1 O15118 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
AKR1C3 P42330 1/20 0.33
HPGD P15428 1/20 0.33
KDM1A O60341 2/20 0.33
RECQL P46063 1/20 0.33
SLC6A3 Q01959 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27834861 0.87 ABCG2 (0.40) ABCG2KMT2AMEN1LMNAMAPT
SCHEMBL6410147 0.84 AKR1C3 (0.45) KMT2AMEN1HTTRAB9ANPC1
SCHEMBL1397476 0.74 ABCG2 (0.53) ABCG2KMT2AMEN1MAPTAKR1C3
SCHEMBL28732347 0.74 ABCG2 (0.53) ABCG2KMT2AMEN1MAPTAKR1C3
SCHEMBL1397156 0.73 CYP2C19 (0.46) KMT2AMEN1LMNAMAPTRAB9A
SCHEMBL2196174 0.71 CYP2C19 (0.34) KMT2AMEN1LMNAMAPTHTT
SCHEMBL27471671 0.71 ABCG2 (0.50) ABCG2KMT2AMEN1POLBNPC1
SCHEMBL27834855 0.70 ABCG2 (0.42) ABCG2KMT2AMEN1LMNAMAPT
SCHEMBL3818255 0.69 AKR1C3 (0.55) ABCG2KMT2AMEN1HTTRAB9A
SCHEMBL9103420 0.69 ABCG2 (0.54) ABCG2KMT2AMEN1MAPTPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2007834-B1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2015-11-04 EP disclosed
EP-2197840-B1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2013-11-06 EP disclosed
EP-2125713-B1 SULPHONIUM SALT PHOTOINITIATORS BASF SE (DE) 2012-04-18 EP disclosed
EP-2197840-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-06-23 EP disclosed
EP-2197839-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-06-23 EP disclosed
EP-2197869-A1 SULPHONIUM SALT INITIATORS BASF SE (DE) 2010-06-23 EP disclosed
EP-2125713-A1 SULPHONIUM SALT PHOTOINITIATORS Ciba SC Holding AG (CH) 2009-12-02 EP disclosed
WO-2009047151-A1 SULPHONIUM SALT INITIATORS BASF SE (CH) 2009-04-16 WO disclosed
WO-2009047152-A1 SULPHONIUM SALT INITIATORS BASF SE (CH) 2009-04-16 WO disclosed
WO-2009047105-A1 SULPHONIUM SALT INITIATORS BASF SE (CH) 2009-04-16 WO disclosed
EP-2007834-A1 SULPHONIUM SALT INITIATORS Ciba Holding Inc. (CH) 2008-12-31 EP disclosed
WO-2008040648-A1 SULPHONIUM SALT PHOTOINITIATORS CIBA HOLDING INC. (CH) 2008-04-10 WO disclosed
EP-1902019-A1 SULPHONIUM SALT INITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. Patent Departement (CH) 2008-03-26 EP disclosed
WO-2007118794-A1 SULPHONIUM SALT INITIATORS CIBA HOLDING INC. (CH) 2007-10-25 WO disclosed
WO-2007003507-A1 SULPHONIUM SALT INITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2007-01-11 WO disclosed
US-20010036591-A1 Iodonium salts as latent acid donors IGM GROUP B.V. (NL) 2001-11-01 US disclosed
US-6306555-B1 RADIATION-SENSITIVE COMPOSITION COMPRISING CATIONICALLY OR ACID-CATALYTICALLY POLYMERISABLE OR CROSSLINKABLE COMPOUND OR COMPOUND THAT INCREASES ITS SOLUBILITY IN DEVELOPER UNDER ACTION OF ACID, AND AT LEAST ONE DIARYLIODONIUM SALT CIBA SPECIALTY CHEMICALS CORP. 2001-10-23 US disclosed