SCHEMBL3818255

SCHEMBL3818255

CO/C(=C/c1ccccc1)C(=O)O

nearest known ligand 0.62

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.55
ABCG2 Q9UNQ0 2/20 0.54
AKR1C1 Q04828 1/20 0.48
ALDH1A1 P00352 3/20 0.47
RECQL P46063 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
HTT P42858 1/20 0.46
TSHR P16473 2/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CYP3A4 P08684 1/20 0.44
CYP2C9 P11712 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3485765 1.00 AKR1C3 (0.55) AKR1C3ABCG2AKR1C1ALDH1A1RECQL
SCHEMBL83065 1.00 AKR1C3 (0.55) AKR1C3ABCG2AKR1C1ALDH1A1RECQL
SCHEMBL8351839 0.98 AKR1C3 (0.53) AKR1C3ABCG2AKR1C1ALDH1A1RECQL
Hydrochloric Acid SCHEMBL10437231 0.98 AKR1C3 (0.53) AKR1C3ABCG2AKR1C1ALDH1A1RECQL
Ammonia Solution, Strong SCHEMBL4743624 0.98 ABCG2 (0.56) AKR1C3ABCG2AKR1C1ALDH1A1RECQL
Acrylic Acid SCHEMBL2468603 0.91 ABCG2 (0.48) AKR1C3ABCG2AKR1C1ALDH1A1RECQL
Cyanamide SCHEMBL5277769 0.89 MCL1 (0.47) AKR1C3ABCG2AKR1C1ALDH1A1RECQL
Tert-Butylbenzene SCHEMBL31552779 0.88 ABCG2 (0.46) AKR1C3ABCG2AKR1C1ALDH1A1RECQL
Monoethanolamine SCHEMBL30202395 0.88 ABCG2 (0.46) AKR1C3ABCG2AKR1C1ALDH1A1RECQL
SCHEMBL9103420 0.88 ABCG2 (0.54) AKR1C3ABCG2AKR1C1ALDH1A1RECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110160390-B Non-contact efficient enhanced heat transfer system and method for pipeline resistance reduction flow 中国石油大学(北京) 2020-05-01 CN claimed
CN-110160390-B Non-contact efficient enhanced heat transfer system and method for pipeline resistance reduction flow 中国石油大学(北京) 2020-05-01 CN disclosed
CN-110160390-B Non-contact efficient enhanced heat transfer system and method for pipeline resistance reduction flow 中国石油大学(北京) 2020-05-01 CN disclosed
EP-2086963-A2 HEPATITIS C VIRUS INHIBITORS Brystol-Myers Squibb Company (US) 2009-08-12 EP disclosed
WO-2008060927-A2 HEPATITIS C VIRUS INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2008-05-22 WO disclosed
EP-0992485-B1 Chiral compounds MERCK PATENT GMBH (DE) 2003-07-30 EP disclosed
US-6495217-B2 LIQUID CRYSTALS MERCK PATENT GMBH (DE) 2002-12-17 US disclosed
US-20020005505-A1 CHIRAL COMPOUNDS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2002-01-17 US disclosed
EP-0992485-A1 Chiral compounds MERCK PATENT GmbH (DE) 2000-04-12 EP disclosed
US-4535130-A SUNSCREEN AGENTS, SKIN CREAMS SOCIETE NATIONALE ELF AQUITAINE (PRODUCTION) (FR) 1985-08-13 US disclosed
US-4435545-A AN EPOXY-CONTAINING POLYOLEFIN OR ACRYLATE IS REACTED WITH SALICYLIC ACID, CINNAMIC ACID OR METHOXYCINNAMIC ACID SOCIETE NATIONALE ELF AQUITAINE (PRODUCTION) (FR) 1984-03-06 US disclosed