Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 18/20 | 0.65 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.65 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5310334 | 0.94 | SLC6A4 (0.61) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5140924 | 0.86 | SLC6A4 (0.77) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5309463 | 0.81 | SLC6A3 (0.46) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL3518513 | 0.79 | SLC6A4 (1.00) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17452479 | 0.78 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL17029605 | 0.77 | SLC6A4 (0.70) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL20459051 | 0.76 | SLC6A4 (0.84) | SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL5308102 | 0.76 | SLC6A4 (0.65) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL15862766 | 0.73 | SLC6A4 (0.68) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL5089843 | 0.73 | SLC6A4 (0.74) | SLC6A4SLC6A3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2974724-A1 | PYRROLIDINE TRIPLE REUPTAKE INHIBITORS | Sunovion Pharmaceuticals Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| EP-2393357-B1 | PYRROLIDINE TRIPLE REUPTAKE INHIBITORS | SUNOVION PHARMACEUTICALS INC (US) | 2015-08-26 | — | — | EP | disclosed |