SCHEMBL1703289

SCHEMBL1703289

N#Cc1ccc(NC(=O)Nc2ccccc2-c2nc3ccccc3c(=O)o2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 7/20 0.51
▸ KDM4E B2RXH2 3/20 0.51
▸ GAA P10253 2/20 0.51
▸ XBP1 P17861 1/20 0.51
▸ KMT2A Q03164 5/20 0.50
▸ MEN1 O00255 4/20 0.50
▸ C1R P00736 7/20 0.46
▸ F2 P00734 1/20 0.46
▸ PLG P00747 1/20 0.46
▸ KLK1 P06870 1/20 0.46
▸ PRSS1 P07477 1/20 0.46
▸ C1S P09871 1/20 0.46
▸ ATM Q13315 1/20 0.46
▸ L3MBTL1 Q9Y468 1/20 0.46
▸ HPGD P15428 3/20 0.46
▸ MAPT P10636 2/20 0.46
▸ LMNA P02545 1/20 0.45
▸ CXCR1 P25024 1/20 0.44
▸ CXCR2 P25025 1/20 0.44
▸ NPC1 O15118 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14560103 0.91 ALDH1A1 (0.59) ALDH1A1KDM4EGAAXBP1KMT2A
SCHEMBL3810516 0.89 KMT2A (0.58) ALDH1A1KDM4EGAAXBP1KMT2A
SCHEMBL14560083 0.86 ALDH1A1 (0.56) ALDH1A1KDM4EGAAXBP1KMT2A
SCHEMBL14560091 0.86 ALDH1A1 (0.62) ALDH1A1KDM4EGAAXBP1KMT2A
SCHEMBL14560100 0.84 KMT2A (0.56) ALDH1A1KDM4EGAAXBP1KMT2A
SCHEMBL14560096 0.83 IGF1R (0.59) ALDH1A1KDM4EGAAXBP1KMT2A
SCHEMBL14560104 0.83 C1R (0.55) ALDH1A1KDM4EGAAXBP1KMT2A
SCHEMBL14560099 0.83 MAPT (0.60) ALDH1A1KDM4EGAAXBP1KMT2A
SCHEMBL14560102 0.82 ALDH1A1 (0.53) ALDH1A1KDM4EGAAXBP1KMT2A
SCHEMBL14560101 0.81 STING1 (0.51) ALDH1A1KDM4EGAAXBP1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101809099-B Novel organic fluorescent sulfonylureido benzo-oxazinone pigments HONEYWELL INT INC 2013-06-19 — — CN disclosed
EP-2195395-B1 NEW ORGANIC FLUORESCENT SULFONYL UREIDO BENZOXAZINONE PIGMENTS HONEYWELL INT INC (US) 2012-04-18 — — EP disclosed
CN-101809099-A Novel organic fluorescent sulfonylureido benzo-oxazinone pigments HONEYWELL INT INC 2010-08-18 — — CN disclosed
US-7740693-B2 E.g., 1-(p-toluenesulfonyl)-3-[2-(4-oxo-4H-benzo[d]-[3.1]oxazine-2-yl)-phenyl]urea; fluorine-free; marking currency, passports, chip cards, checks, check cards, credit cards, debit cards, identity cards, certificates, bank notes, and postal items HONEYWELL INTERNATIONAL INC. 2010-06-22 — — US disclosed
EP-2195395-A2 NEW ORGANIC FLUORESCENT SULFONYL UREIDO BENZOXAZINONE PIGMENTS Honeywell International Inc. (US) 2010-06-16 — — EP disclosed
WO-2009045988-A2 NEW ORGANIC FLUORESCENT SULFONYL UREIDO BENZOXAZINONE PIGMENTS HONEYWELL INTERNATIONAL INC. (US) 2009-04-09 — — WO disclosed
US-20090085344-A1 E.g., 1-(p-toluenesulfonyl)-3-[2-(4-oxo-4H-benzo[d]-[3.1]oxazine-2-yl)-phenyl]urea; fluorine-free; marking currency, passports, chip cards, checks, check cards, credit cards, debit cards, identity cards, certificates, bank notes, and postal items HONEYWELL INTERNATIONAL INC. 2009-04-02 — — US disclosed
US-7192471-B2 producing fluorescence when excited by ultraviolet light; Especially for security applications HONEYWELL INTERNATIONAL INC. (US) 2007-03-20 — — US disclosed
US-7192471-B2 producing fluorescence when excited by ultraviolet light; Especially for security applications HONEYWELL INTERNATIONAL INC. (US) 2007-03-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090085344-A1 E.g., 1-(p-toluenesulfonyl)-3-[2-(4-oxo-4H-benzo[d]-[3.1]oxazine-2-yl)-phenyl]urea; fluorine-free; marking currency, passports, chip cards, checks, check cards, credit cards, debit cards, identity cards, certificates, bank notes, and postal items H1-10, KDM4C, H1-4 ALDH1A1 718/4885KDM4E 15/4885GAA 1453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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