SCHEMBL1703296

SCHEMBL1703296

CCOC(CC(=O)c1ccccc1)=NO

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.53
NPC1 O15118 5/20 0.53
MEN1 O00255 4/20 0.53
SMN1; SMN2 Q16637 4/20 0.52
MAPT P10636 2/20 0.52
CYP3A4 P08684 2/20 0.52
HPGD P15428 2/20 0.52
KDM4E B2RXH2 1/20 0.52
ALOX15 P16050 1/20 0.52
CES1 P23141 1/20 0.52
MAPK1 P28482 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
RAB9A P51151 4/20 0.51
PTPN1 P18031 1/20 0.46
ERCC5 P28715 1/20 0.46
FEN1 P39748 1/20 0.46
POLB P06746 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
ALDH1A1 P00352 2/20 0.45
GAA P10253 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL124577 0.79 KMT2A (0.59) KMT2ANPC1MEN1SMN1; SMN2MAPT
SCHEMBL17433641 0.77 KMT2A (0.57) KMT2ANPC1MEN1SMN1; SMN2MAPT
SCHEMBL17433632 0.77 KMT2A (0.57) KMT2ANPC1MEN1SMN1; SMN2MAPT
SCHEMBL28048832 0.77 KMT2A (0.57) KMT2ANPC1MEN1SMN1; SMN2MAPT
SCHEMBL17433663 0.77 KMT2A (0.57) KMT2ANPC1MEN1SMN1; SMN2MAPT
SCHEMBL17433560 0.77 KMT2A (0.57) KMT2ANPC1MEN1SMN1; SMN2MAPT
SCHEMBL6753757 0.77 KMT2A (0.57) KMT2ANPC1MEN1SMN1; SMN2MAPT
SCHEMBL28792148 0.77 KMT2A (0.57) KMT2ANPC1MEN1SMN1; SMN2MAPT
SCHEMBL31439645 0.77 KMT2A (0.57) KMT2ANPC1MEN1SMN1; SMN2MAPT
SCHEMBL28048838 0.77 KMT2A (0.57) KMT2ANPC1MEN1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1806408-B1 Process for producing amino acid derivatives from hydroxyimino acids AJINOMOTO KK (JP) 2012-04-18 EP disclosed
US-8043836-B2 Contacting Citrobacter/Escherichia and/or enzyme with a hydroxyimino acid; for biosynthesis of tryptophan AJINOMOTO CO., INC. (JP) 2011-10-25 US disclosed
US-20080193984-A1 Process For Producing Amino Acid Derivative From Hydroxyimino Acid AJINOMOTO CO., INC. (JP) 2008-08-14 US disclosed
CN-101035903-A Process for producing amino acid derivative from hydroxyimino acid AJINOMOTO KK (JP) 2007-09-12 CN disclosed
EP-1806408-A1 PROCESS FOR PRODUCING AMINO ACID DERIVATIVE FROM HYDROXYIMINO ACID Ajinomoto Co., Inc. (JP) 2007-07-11 EP disclosed